Insulin Resistance Clinical Trial
— VIVOOfficial title:
The Effect of Vinegar Consumption on Visceral Fat and Blood Glucose Concentration
Verified date | August 2019 |
Source | Arizona State University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this study is to test the potential ability of vinegar to significantly
decrease visceral fat in healthy adults with "central obesity". During the 8-week trial,
participants will either consume a low-dose vinegar pill (control treatment) or a vinegar
drink twice per day.
Research Aim and Hypothesis H1 Daily vinegar consumption will be associated with loss in
visceral fat (as measured by DXA) after 8 weeks compared to the placebo treatment
(low-vinegar pill) in a group of healthy adults with "central obesity".
H2 Daily vinegar consumption will be associated with a decrease in abdominal circumference
after 8 weeks compared to the placebo treatment (low-vinegar pill) in a group of healthy
adults with "central obesity".
Status | Completed |
Enrollment | 102 |
Est. completion date | August 15, 2018 |
Est. primary completion date | August 15, 2018 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 45 Years |
Eligibility |
Inclusion Criteria: - Nonsmoking - Not pregnant or lactating if female - No active disease state or medication use affecting blood glucose or cholesterol (additionally, individuals on digoxin or diuretics will be excluded but other medications in use >3 months will be allowed) - No food restrictions or special diet - BMI range: 22-35 - Waist circumference >34 (women) and >39 (males) - Sedentary (exercising < 3 days/week) Exclusion Criteria: - Unwilling to take a vinegar supplement daily for 8 week or follow other aspects of study protocol - Recent abdominal surgery or condition causing abdominal discomfort/distention (such as acid reflux, ascites, pancreatitis, diverticulitis/diverticulosis, Crohn's disease, and/or irritable bowel syndrome) |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Carol Johnston |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | visceral adiposity | visceral fat as measured by DXA | change after 8 weeks of treatment | |
Secondary | tooth erosion | dental exam using Basic Erosion Wear Examination (BEWE) | change after 8 weeks of treatment | |
Secondary | insulin resistance | measurement of insulin resistance using HOMA-IR (fasting glucose and fasting insulin index) | change after 8 weeks of treatment |
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