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NCT03584607 Clinical Trial

Insulin- and Glucose Metabolism in Pulmonary Arterial Hypertension

Insulin Resistance Clinical Trial

Official title:
Insulin- and Glucose Metabolism in Pulmonary Arterial Hypertension - a Pilot Study

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03584607
Other study ID # 29-066 ex 16/17
Secondary ID
Status Completed
Phase
First received
Last updated
Start date December 20, 2017
Est. completion date February 11, 2019

Study information
Verified date January 2020
Source Medical University of Graz
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Insulin resistance is a key mechanism in metabolic disorders, which has also been implicated in the development of pulmonary hypertension. In this pilot study, the investigators´ goal is to directly determine insulin sensitivity in idiopathic pulmonary arterial hypertension patients and to compare the results with data from healthy controls.

Recruitment information / eligibility
Status Completed
Enrollment 10
Est. completion date February 11, 2019
Est. primary completion date February 11, 2019
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 90 Years
Eligibility Inclusion Criteria:

- signed informed consent form

- patients with idiopathic or hereditary pulmonary hypertension / healthy controls

Exclusion Criteria:

- premenopausal women

- other relevant lung disease

- relevant left heart disease

- untreated systemic hypertension

- Diabetes mellitus

- pulmonary hypertension other than idiopathic or hereditary form

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Austria Medical University Graz, Division of Pulmonology Graz Steiermark

Sponsors (1)
Lead Sponsor Collaborator
Medical University of Graz

Country where clinical trial is conducted

Austria, 

Outcome
Type Measure Description Time frame Safety issue
Primary Insulin resistance Determination of insulin sensitivity using hyperinsulinemic-euglycemic clamp technique 1 day
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