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Injury clinical trials

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NCT ID: NCT06142110 Completed - Injury Clinical Trials

The Relationship Between Functional Movement and Respiratory Muscle Strength

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

Functional Movement Screen (FMS) is a battery used for injury prediction, identifying asymmetry and weak connections in basic functional movement patterns. The muscles assessed in FMS are also respiratory muscles. Therefore, FMS scores were thought to be related to respiratory muscle strength. The aim of our study was to examine the relationship between Functional Movement Screen and respiratory muscles strength in professional football players and sedentary individuals.

NCT ID: NCT04780867 Completed - Stress Clinical Trials

Psychological and Lifestyle Factors on Health Outcomes

Start date: October 19, 2020
Phase: N/A
Study type: Interventional

Psychosocial and lifestyle factors in Army recruits likely contribute to increased susceptibility to infection and injury during basic Army training. The primary aim of this study is to assess the influence of psychosocial and lifestyle factors at the start of basic Army training on immune health (e.g. respiratory infection and antibody response to influenza vaccination) and injury during training, in an observational design. A secondary aim is to establish whether changes in psychosocial and lifestyle factors during training impact immune health (e.g. response to hepatitis B vaccination). Using an interventional design, participants will be randomly allocated into two experimental groups: (i) Routine vaccination group: to receive first hepatitis B vaccination at initial medical assessment upon entry to basic training and second hepatitis B vaccination 1 month later; (ii) Delayed vaccination group: to receive first hepatitis B vaccination during week 5 of training and second hepatitis B vaccination 1 month later.

NCT ID: NCT04646876 Completed - Clinical trials for Traumatic Brain Injury

Mgso4 as Neuroprotective in Post Traumatic Brain Injury

Start date: May 2, 2019
Phase: Phase 3
Study type: Interventional

The aim of this study is to assess the potential role of magnesium sulphate (MgSo4) as a neuroprotective agent using the Glasgow outcome scale following moderate and severe traumatic brain injury.

NCT ID: NCT04059575 Completed - Injury Clinical Trials

Is Kinesio Taping Application Effective on Decreasing Injury Risk for Tennis Players

Start date: September 24, 2020
Phase: N/A
Study type: Interventional

Research design: The study protocol was approved and required permissions were taken from related tennis club officials, and a written consent was obtained from all the participants' parents about the study. Thirty-three young tennis players aged between 9 and 12 were included in our study. Assessment were done bare (no tape), after 45 min of performance plus kinesio taping application (PP application) and after 45 min of gold text FP kinesio taping application (GT application). We were randomly taped with either PP or GT taping applications using an online random allocation software program (GraphPad Software QuickCalcs, GraphPad Software Inc., La Jolla, CA, USA). Thirty min of rest was given between 2 taping applications after the removal of the first tape. One participant was not able to complete the second taping procedure. PP and GT taping applications were done by using kinesio taping muscle facilitation techniques to Quadriceps and Gastrosoleus muscles. I-shaped tape with a tension of 10-35% was used for muscle facilitation. All patients were assessed by an experienced physiotherapist, and the tapings were done by another experienced physiotherapist in order to provide a single blind structure of the study.

NCT ID: NCT02971072 Completed - Pain Clinical Trials

Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy

Start date: July 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to examine deficits in activation and motor patterns, as well as central drive in patients with rotator cuff tendinopathy. There are three specific aims: (1) determine the effect of acute pain relief on rotator cuff muscle activation in patients with rotator cuff tendinopathy, (2) determine the effect of exercise on rotator cuff muscle activation in patients with rotator cuff tendinopathy, and (3) compare rotator cuff muscle activation between patients with rotator cuff tendinopathy and healthy controls.

NCT ID: NCT02934633 Completed - Injury Clinical Trials

Parent Training in Child Safety Practices

BabySafety_2
Start date: August 2006
Phase: Phase 2
Study type: Interventional

This project completed an intervention designed to teach parents of children aged 0-2 years of age how to prevent injuries to their child. The intervention consisted of a two DVD package with information on creating a safe home environment and correctly choosing and installing an appropriate car safety seat. The study hypothesis was that parents who used the intervention would score significantly higher on measures of knowledge, motivation, intention and self-efficacy in implementing injury prevention strategies.

NCT ID: NCT02331121 Completed - Injury Clinical Trials

Multimedia First Aid Program for Families

FirstAid_2
Start date: June 2012
Phase: N/A
Study type: Interventional

Unintentional injuries are the leading cause of death for children and infants under 14 years of age. Many of these deaths are preventable, in part by promoting injury prevention behaviors but also by administering effective emergency first aid techniques until advanced care arrives. This project created a web site program that paired video-based instruction with interactive skills training to teach parents of children birth to 12 years old basic first-aid and CPR skills, and that included the option to practice skills as needed.

NCT ID: NCT02203968 Completed - Trauma Clinical Trials

Fibrinogen in the Initial Resuscitation of Severe Trauma (FiiRST)

FiiRST
Start date: October 2014
Phase: Phase 1/Phase 2
Study type: Interventional

Trauma is the leading cause of death in people 44 years of age or younger. After major trauma, such as following high-speed motor vehicle collision, bleeding coupled with clotting defects is responsible for most of deaths in the first hours of hospital admission. Of note, these bleeding-related deaths are potentially preventable. Accordingly, the initial in-hospital management of severely injured patients focuses on stopping bleeding, replacing blood loss and correcting clotting defects. Recently, animal and human research demonstrated that one of the major clotting defects following injury and bleeding is the drop in blood levels of fibrinogen (a clotting factor), which is detected on hospital admission in severely injured patients. These low fibrinogen levels are associated with increased blood transfusion and death. However, in North America, the standard of care for replacing low fibrinogen requires the use of cryoprecipitate, which is a frozen blood product with long preparation time, and similarly to other blood products, carries the risk of viral transmission and transfusion complications. Alternately, many Europeans countries where cryoprecipitate has been withdrawn from the market due to safety concerns, use fibrinogen concentrate. Fibrinogen concentrate undergoes pathogen inactivation, which is a process to eliminate the risk of transmitting viruses, bacteria and parasites, is likely a safer and faster alternative to cryoprecipitate. In Canada, fibrinogen concentrate is licensed for congenital low fibrinogen only. Although preliminary data suggest that fibrinogen supplementation in trauma is associated with reduced bleeding, blood transfusion, and death, the feasibility, safety and efficacy of early fibrinogen replacement remains unknown. We proposed to conduct a feasibility randomized trial to evaluate the use of early fibrinogen concentrate against placebo in injured patients at our trauma centre. A pilot trial is necessary to demonstrate the feasibility of rapidly preparing, delivering, and infusing fibrinogen concentrate as an early therapy to prevent excessive bleeding in trauma. This feasibility trial will provide preliminary safety and clinical outcome data to inform the design of larger trials; which ultimately aims to prevent bleeding-related deaths in the trauma population.

NCT ID: NCT02165137 Completed - Trauma Clinical Trials

Management of Major Trauma Patients at Aarau Trauma Center - Evaluation of Processes and Patient Outcome

Start date: January 2010
Phase:
Study type: Observational [Patient Registry]

Quality control and improvement project: Assessment and analysis of processes and outcome in trauma emergency room and major trauma patients at the Aarau trauma center (cantonal hospital) with regard to initial emergency management, hospital processes and short- and long-term (1-and 2-year) outcome of patients (subjective and objective). Comparison of processes and outcome pre- and post- project initiative. Benchmarking with the literature and by participation in the German and Swiss Trauma registry each.

NCT ID: NCT02011412 Completed - Trauma Clinical Trials

Intermountain Risk Score and Trauma

Start date: October 2013
Phase: N/A
Study type: Observational

The investigators hypothesize that a risk score composed of age, sex, and the components of commonly ordered laboratory panels will be predictive of mortality in trauma patients, and will help improve clinicians' ability to make more accurate mortality predictions at the time of admission.