Inflammation Clinical Trial
Official title:
Oxidative Stress and Inflammatory Processes in Selected Neoplasms in the Group of Oncological Patients Examined With the FDG PET/CT Method.
NCT number | NCT03470857 |
Other study ID # | KB 363/2017 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | June 19, 2017 |
Est. completion date | June 30, 2021 |
Verified date | September 2022 |
Source | Nicolaus Copernicus University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The research aims to determine the parameters of oxidative stress and inflammatory processes and compare these parameters with the image obtained using positron emission tomography (PET) with 2-deoxy-2-[fluorine-18]fluoro- D-glucose (18F-FDG) integrated with computed tomography (CT) in the group of oncological patients.
Status | Completed |
Enrollment | 83 |
Est. completion date | June 30, 2021 |
Est. primary completion date | June 30, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - sign informed consent form for participation in the study Exclusion Criteria: - other diseases, - bad feeling of the studied individual on the day of the study, - the participants will not be minor and incapacitated persons, soldiers, prisoners and persons dependent in any way from the investigators. |
Country | Name | City | State |
---|---|---|---|
Poland | Department of Nuclear Medicine of Center Oncology in Bydgoszcz | Bydgoszcz | Kujawsko-Pomorskie |
Poland | Department of Positron Emission Tomography and Molecular Diagnostics, Collegium Medicum of Nicolaus Copernicus University | Bydgoszcz | Kujawsko Pomorskie |
Poland | The Chair of Medical Biology, Collegium Medicum of Nicolaus Copernicus University | Bydgoszcz | Kujawsko-Pomorskie |
Lead Sponsor | Collaborator |
---|---|
Nicolaus Copernicus University |
Poland,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Superoxide Dismutase | Antioxidant enzyme | 1 day (Single measurement) | |
Primary | Catalase | Antioxidant enzyme | 1 day (Single measurement) | |
Primary | Glutathione Peroxidase | Antioxidant enzyme | 1 day (Single measurement) | |
Primary | Thiobarbituric acid reactive substances (Malondialdehyde) | Secondary lipid peroxidation product | 1 day (Single measurement) | |
Primary | Conjugated Dienes | Primary lipid peroxidation product | 1 day (Single measurement) | |
Primary | 8-iso-Prostaglandin F2alpha | Secondary lipid peroxidation product | 1 day (Single measurement) | |
Primary | 4-Hydroxynonenal | Secondary lipid peroxidation product | 1 day (Single measurement) | |
Primary | Total Antioxidant Capacity | Total antioxidant potential of blood serum in the participant | 1 day (Single measurement) | |
Primary | Acid Phosphatase | Lysosomal enzyme | 1 day (Single measurement) | |
Primary | Cathepsin D | Lysosomal enzyme | 1 day (Single measurement) | |
Primary | Arylsulfatase | Lysosomal enzyme | 1 day (Single measurement) | |
Primary | Alpha-1-Antitrypsin | Serine protease inhibitor | 1 day (Single measurement) | |
Primary | Vitamins A and E | Low molecular weight antioxidants | 1 day (Single measurement) | |
Secondary | FDG PET/CT scanning | Positron emission tomography with 2-deoxy-2-[fluorine-18]fluoro- D-glucose integrated with computed tomography | 1 day (Single measurement) |
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