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Infection clinical trials

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NCT ID: NCT03785938 Not yet recruiting - Pediatric Cancer Clinical Trials

Mucositis and Infection Reduction With Liquid Probiotics in Children With Cancer

MaCROS
Start date: January 20, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the feasibility of an randomised-controlled trial to investigate the efficacy of liquid probiotics to prevent or reduce mucositis and infection in children diagnosed with cancer who are undergoing treatment with regimes likely to cause mucositis.

NCT ID: NCT03784807 Recruiting - Clinical trials for Prosthetic Joint Infection

New Strategies for Biofilm Related Infections

Diafilm
Start date: November 2, 2018
Phase:
Study type: Observational

This study aims to develop new assays for synovial fluid analysis able to improve diagnosis of prosthetic joint infections. In particular, use of synovial calprotectin as marker of infection, confocal laser scanning microscopy (CLSM) analysis and methods to assess antimicrobial susceptibility will be evaluated in synovial fluids collected from patients with septic and aseptic failure of the prosthetic implant.

NCT ID: NCT03781206 Recruiting - Clinical trials for Stoma Site Infection

Negative Pressure Wound Therapy for Wound Healing After Stoma Reversal

NESTOR
Start date: July 18, 2019
Phase: N/A
Study type: Interventional

Stoma reversal is associated with high incidence of post-surgical complications, including Surgical Site Infections (SSI). Negative Pressure Wound Therapy (NPWT) has been successfully applied to surgical wound management, reducing the SSIs incidence. This is a randomized open-label trial to assess the efficacy of NPWT in decreasing the rate of SSI after stoma reversal.

NCT ID: NCT03781024 Enrolling by invitation - Diabetic Foot Ulcer Clinical Trials

A Subjective Observational Study of Patients Using Medicated Footbath/Footwash Treatment in Podiatry Care

Start date: December 1, 2018
Phase:
Study type: Observational

The purpose of this study is to evaluate the level of relief perceived by patients using medicated footbath/footwash with or without an oral medication for the treatment of podiatry issues.

NCT ID: NCT03780439 Completed - Gastric Cancer Clinical Trials

Procalcitonin to Predict Infection After Gastrectomy for Gastric Cancer

Start date: June 1, 2018
Phase:
Study type: Observational

To investigate the diagnostic accuracy of procalcitonin as an early predictor of infection after radical gastrectomy for gastric cancer.

NCT ID: NCT03780140 Approved for marketing - Clinical trials for Bacterial Infections

Expanded Access to Cefiderocol for the Intravenous Treatment of Severe Gram Negative Bacterial Infections

Start date: n/a
Phase:
Study type: Expanded Access

Expanded access may be provided for cefiderocol for qualified patients who have limited treatment options and are not eligible for a clinical trial.

NCT ID: NCT03780114 Not yet recruiting - Infection Control Clinical Trials

Knowledge, Attitude and Practice Survey for Egyptian Dentists About Infection Control in Pediatric Dental Clinics

case-only
Start date: February 1, 2019
Phase:
Study type: Observational

This study is designed to gather information about knowledge of pediatric dentistry interns towards infection control procedures in pediatric dental clinics, also about their attitude towards the rules and guidelines of infection control, and finally their practice to these guidelines to achieve the ultimate infection control in pediatric dental clinics.

NCT ID: NCT03776994 Active, not recruiting - Clinical trials for Nervous System Diseases

Venezuelan Equine Encephalitis Monovalent Virus-Like Particle Vaccine

VEEV
Start date: July 17, 2018
Phase: Phase 1
Study type: Interventional

The primary objective of the study is to evaluate the safety and immunogenicity of non-adjuvanted and adjuvanted monovalent VEE VLP Vaccine in healthy adults (ages 18-50 years) when administered via intramuscular (IM) injection at escalating doses of 2 μg, 10 μg, and 20 μg as a 2-dose primary series (Day 0, Day 28) with a Day 140 booster dose. The secondary objective of the study is to evaluate immunogenicity of the vaccine at the aforementioned time points

NCT ID: NCT03772769 Completed - Clinical trials for Odontogenic Deep Space Neck Infection

Diagnostic Modalities for Severe Odontogenic Infections Using Rapid, Target Enriched Multiplex PCR (TEM- PCR) by Diatherix

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate the sensitivity and specificity of the Target Enriched Multiplex (TEM) polymerase chain reaction (PCR) platform for the rapid molecular diagnosis and treatment of odontogenic deep space neck infections.

NCT ID: NCT03770533 Completed - Clinical trials for Patients Presenting With Suspicion of Infection to the ED

Identifying Patients With Suspicion of Infection in the ED Who Have Low Disease Severity Using MR-proADM - Pilot Study

IDEAL
Start date: December 14, 2018
Phase: N/A
Study type: Interventional

Emergency departments (ED) are becoming increasingly over-crowded, with patients facing prolonged waiting times. Therefore, a safe and rapid assessment that identifies patients with low severity that could be treated as outpatients is essential for improving the workflow within the ED. The rationale of this IDEAL study is to provide guidance to safely decrease the number of hospital admissions through identification of low risk patients with the biomarker MR-proADM. This will be tested in a pilot study first.