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Infection clinical trials

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NCT ID: NCT02886637 Completed - Clinical trials for Acinetobacter Baumannii Infection

Effects of Immune Function on Prognositic Outcome in Critical Ill Patients With Acinetobacter Baumannii Infection

Start date: July 2015
Phase: N/A
Study type: Observational

The purpose of the present study is to evaluate the effects of immune function on prognositic outcome in critical ill patients with Acinetobacter baumannii infection.

NCT ID: NCT02886143 Completed - Clinical trials for Urinary Tract Infections

Effect of Active vs. Passive Voiding Trials on Time to Discharge, Urinary Tract Infection, and Urinary Retention

Start date: October 2015
Phase: Phase 3
Study type: Interventional

Urinary retention is a common problem, particularly in hospitalized patients. When a Foley catheter is removed, a patient must be monitored for urinary retention. The usual method is a passive voiding trial where the catheter is removed, the bladder fills with urine and the patient is monitored for voiding over approximately 6 hours. Another option is an active voiding trial where the bladder is filled with saline before the catheter is removed and the patient is immediately assisted to void. This study seeks to determine the effect of active vs passive voiding trials on time to hospital discharge, rate of urinary tract infections, and rate or urinary retention in the general hospitalized population.

NCT ID: NCT02884752 Completed - Clinical trials for Campylobacter Infections

Retrospective Study of Bone Infection Due to Campylobacter Spp

CAMPYLO
Start date: December 2014
Phase: N/A
Study type: Observational

Only 24 cases of Campylobacter bone and joint infection (BJI) have been reported worldwide between 1955 and 2008. Between 2010 and 2012, 7 cases were observed in two University hospitals in France. This increasing number of cases raises several issues. Are they the consequences of better detections and reporting, or are they reflecting any epidemiologic changes? For answering these questions, we performed a 10 year (2002-2012) retrospective multicenter (6 centers) study on BJI (native and implanted joints) due to Campylobacter species.

NCT ID: NCT02877927 Completed - Clinical trials for Bacterial Infections

Oral Omadacycline vs. Oral Linezolid for the Treatment of ABSSSI

Start date: August 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of omadacycline as compared to linezolid in the treatment of adults with acute bacterial skin and skin structure infections.

NCT ID: NCT02875808 Completed - Clinical trials for Intrathecal Infection

Cerebrospinal Fluid IL-6, IL-8 and PCT as Early Marker of an Intrathecal Infection in Neurosurgical Patients

Start date: August 1, 2014
Phase:
Study type: Observational

The value of CSF IL-6, IL-8 and Procalcitonin in detecting an early diagnosis of intrathecal infection in neurosurgical patients with an external ventricular drainage is evaluated.

NCT ID: NCT02870101 Completed - Clinical trials for Sexually Transmitted Infections

Performance of Nucleic Acid Amplification Tests for the Detection of NG and CT

pNAAT
Start date: April 10, 2017
Phase: N/A
Study type: Interventional

The purpose of this study was to use participant samples to simultaneously evaluate three nucleic acid amplification tests (NAATs) diagnostic platforms.

NCT ID: NCT02868242 Completed - Clinical trials for Hepatitis C Virus Infection

Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed Dose Combination in the Treatment of Hepatitis C Virus (HCV) Infection in Pediatric Participants Undergoing Cancer Chemotherapy

Start date: August 28, 2016
Phase: Phase 2
Study type: Interventional

The primary objectives of this study are to evaluate the efficacy, safety, and tolerability of ledipasvir/sofosbuvir (LDV/SOF) in treating hepatitis C virus (HCV) infection in pediatric participants who are undergoing cancer chemotherapy.

NCT ID: NCT02865616 Completed - Clinical trials for Clostridium Difficile Infection

MET-2 Clinical Study for Recurrent Clostridium Difficile Infection (CDI)

Start date: October 27, 2017
Phase: Phase 1
Study type: Interventional

MET-2 clinical study is an Open label, single center, multiple dose pilot study of 19 patients. The study is designed to measure the resolution of diarrhea as well as the feasibility of administration and safety of MET-2 for the treatment of recurrent CDI in patients who have experienced at least two prior episodes of CDI and have developed recurrence after having completed standard-of care oral antibiotic therapy to treat CDI.

NCT ID: NCT02862795 Completed - HPV Infection Clinical Trials

Human Papillomavirus Anal Infection

PAPILLAN
Start date: April 2012
Phase: N/A
Study type: Interventional

Human papillomavirus (HPV) are involved in up to 95 % of anal canal neoplastic lesions. Little is known about HPV carriage in anal canal previous to cancer occurrence in the population and pre-neoplastic lesions, and their risk factors. PAPILLAN is a prospective study that aims to study HPV infection (HPV low grade and high grade genotypes) prevalence in anal canal in a population non selected by its HIV status. In that purpose patients are prospectively recruited in a french university hospital gastroenterology unit and anal smears are collected during a colonoscopy with cytobrush.

NCT ID: NCT02862262 Completed - Clinical trials for Bordetella Parapertussis Infection

A Multi-Site Clinical Evaluation of the ARIES Bordetella Assay in Symptomatic Patients

Start date: July 2016
Phase: N/A
Study type: Interventional

A three-arm, multi-site clinical evaluation of the ARIES Bordetella Assay for the detection and identification of Bordetella pertussis (B. pertussis) and Bordetella parapertussis (B. parapertussis) nucleic acids in prospectively collected, de-identified, left-over clinical specimens; banked, pre-selected clinical specimens; and contrived specimens.