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NCT ID: NCT01007487 Completed - Clinical trials for Surgical Site Infection

Plastic Wound Retractors and Bacterial Translocation in Abdominal Surgery

Start date: January 2008
Phase: N/A
Study type: Observational

Hypothesis: Plastic wound retractors reduce passage of bacteria from the abdomen to the surgical incision site in abdominal surgery Currently, plastic wound retractors are used in abdominal surgery to facilitate access to the abdominal cavity. This study aims to establish whether they also prevent bacteria crossing from the abdominal cavity to the surgical incision site. Patients undergoing abdominal surgery in which a plastic wound retractor (Alexis®)is used are eligible for inclusion in the study. Swabs are taken from the inside and the outside of the plastic wound retractor prior to removing the retractor from the abdomen. The bacterial flora from swabs taken inside and outside the plastic wound protector are then compared to see if there is any difference between inside and outside the retractor. Bacteria are classified as 'enteric'(i.e. from the gastrointestinal tract) or 'skin' bacteria, depending on their usual location. The study aims to establish whether a plastic wound retractor (Alexis®) reduces translocation of enteric bacteria to the surgical incision site.

NCT ID: NCT01007396 Completed - Clinical trials for Latent Tuberculosis Infection

Diagnosis of Tuberculosis Infection in Health Care Workers Using Ex-vivo Interferon-gamma Assay

Start date: January 2008
Phase: N/A
Study type: Interventional

The present study was to evaluate the usefulness of a whole-blood interferon-r release assays (IGRAs) as diagnostic tool of the latent tuberculosis infection for healthcare workers.

NCT ID: NCT01006629 Completed - Clinical trials for Congenital Heart Disease

Palivizumab for Prevention of Severe Respiratory Syncytial Virus Infection in Russian Children

Start date: November 2009
Phase: Phase 2/Phase 3
Study type: Interventional

100 Russian children of 2 years of age and less in high-risk populations (preterm, and/or with heart and lung problems) will receive palivizumab (Synagis) 15 mg/kg intramuscularly as prophylaxis to severe respiratory syncytial virus (RSV) infection in order to study the safety and efficacy of the drug in Russian subjects.

NCT ID: NCT01003587 Active, not recruiting - Clinical trials for Cardiovascular Disease

Promoting Evidence-Based Decision-Making in India: District Evaluation Study on Health

DESH
Start date: July 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the impact of disseminating information on comparative performance, along with actionable messages on how to improve health outcomes, to district-level decision-makers in India using a randomized, controlled design. This information should improve prioritization of health services by district health officers, budget allocation for health, and implementation of priority health services at the district level.

NCT ID: NCT01002612 Completed - HIV Infections Clinical Trials

Reassessment of the Nutritional Status in Thai Orphans Living With HIV in a Family Style Community

TACHIN003-1
Start date: December 2007
Phase: N/A
Study type: Observational

To reassess nutritional status of HIV-infected Thai children living in the family style community after receiving nutrition support program for 6 months.

NCT ID: NCT01000818 Completed - HIV Infections Clinical Trials

A Study to Evaluate the Effect of Famotidine and Omeprazole on MK0518 (Raltegravir) Pharmacokinetics in Human Immunodeficiency Virus (HIV)-Infected Patients (0518-054)

Start date: June 2008
Phase: Phase 1
Study type: Interventional

An open-label, 3-period, fixed-sequence study in a panel of 18 HIV-infected patients on MK0518 as part of a stable treatment regimen for HIV.

NCT ID: NCT00999622 Completed - Infection Clinical Trials

Study of Blood Samples and Risk of Infection in Patients With Newly Diagnosed Malignant Supratentorial Astrocytoma

Start date: July 2004
Phase: N/A
Study type: Observational

RATIONALE: Gathering information over time from laboratory tests of patients with newly diagnosed malignant supratentorial astrocytoma may help doctors learn more about the effect of treatment on white blood cell count and the risk of infection. PURPOSE: This clinical trial is studying blood samples and risk of infection in patients with newly diagnosed malignant supratentorial astrocytoma.

NCT ID: NCT00998907 Completed - Wound Infection Clinical Trials

PDS*Plus and Wound Infections After Laparotomy

PDS*plus
Start date: September 2009
Phase: N/A
Study type: Interventional

The aim of this study is to ascertain if the use of PDS plus® reduces the number of wound infections and incisional hernia after midline and transverse laparotomy comparing to polyglactin suture.

NCT ID: NCT00998309 Completed - Clinical trials for Bacterial Infections

Zithromax-SR 2g, Special Investigation (Regulatory Post Marketing Commitment Plan)

Start date: October 2009
Phase: N/A
Study type: Observational

To collect the efficacy and safety information of Zithromax-SR related to their appropriate use in daily practice.

NCT ID: NCT00993148 Completed - HIV Infections Clinical Trials

Maraviroc Plus Darunavir/Ritonavir for Treatment-Naïve Patients Infected With R5-tropic HIV-1

MIDAS
Start date: May 2010
Phase: Phase 2
Study type: Interventional

The objective of this study is to evaluate the safety and efficacy of a novel combination antiretroviral therapy regimen consisting of maraviroc plus darunavir/ritonavir in treatment-naive patients infected with R5-tropic HIV-1. The hypothesis is that in treatment-naive subjects infected with R5-tropic HIV-1, combination antiretroviral therapy with maraviroc plus darunavir/ritonavir is well tolerated and efficacious.