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Infection clinical trials

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NCT ID: NCT02037984 Completed - Clinical trials for Pneumococcal Infections

Safety, Tolerability and Immunogenicity of V114 in Healthy Adults and Infants (V114-004)

Start date: January 28, 2014
Phase: Phase 1/Phase 2
Study type: Interventional

This study is designed to assess the safety, tolerability, and immunogenicity of 5 different formulations of V114 in healthy adults and infants. Adults only will be enrolled in Period 1 and infants only will be enrolled in Period 2; Period 1 will complete prior to the start of Period 2.

NCT ID: NCT02036255 Completed - Infection Clinical Trials

Prevention of Dialysis Catheter Malfunction With Prophylactic Use of a Taurolidine Containing Urokinase

Start date: May 2015
Phase: Phase 3
Study type: Interventional

The objective of our study is to investigate whether the substitution of the standard locking solution with a locking solution containing taurolidine and urokinase weekly (Taurolock ™ U 25,000 - www.taurolock.com ) reduces the rate of catheter dysfunction in hemodialysis patients with a history of TCC dysfunction requiring urokinase therapy.

NCT ID: NCT02035410 Completed - Infection Clinical Trials

Decrease Implantation Site INFECTION (DISINFECTION I): a Randomized Controlled Trial

Start date: December 2013
Phase: N/A
Study type: Interventional

Cardiovascular implantable electronic device (CIED) infections have been increasing out of proportion to the number of devices implanted We investigated recent trends and possible causes of the increasing numbers of Cardiovascular implantable electronic device infections.

NCT ID: NCT02034890 Withdrawn - Clinical trials for Urinary Tract Infection

Intravesical Instillation of Hyaluronic Acid to Decrease Incidence of Urinary Tract Infection

Start date: July 2015
Phase: Phase 4
Study type: Interventional

Prospective trial which includes instillation of intravesical hyaluronic acid in an attempt to reduce the incidence of urinary tract infections in patients after orthotopic neobladder reconstruction.

NCT ID: NCT02034279 Terminated - Pneumonia Clinical Trials

The INFECIR-2 Albumin Prevention Study

INFECIR2
Start date: May 2014
Phase: Phase 4
Study type: Interventional

The aim of this study is to evaluate whether albumin administration improves short-term survival in patients with advanced cirrhosis and bacterial infections other than Spontaneous Bacterial Peritonitis (SBP).

NCT ID: NCT02034162 Completed - Helminth Infections Clinical Trials

A Study to Assess the Efficacy and Safety of Mebendazole for the Treatment of Helminth Infections in Pediatric Participants

Start date: December 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of mebendazole compared with placebo in pediatric participants with Helminth infections.

NCT ID: NCT02033187 Completed - Clinical trials for Healthcare Associated Infections

Daily Chlorhexidine Bathing and Infection Rates in Critically-ill Patients

Start date: July 2012
Phase: Phase 4
Study type: Interventional

Healthcare-associated infections are a major cause of morbidity among critically ill patients. Bathing critically ill patients with cloths impregnated with the broad-spectrum antimicrobial agent chlorhexidine-gluconate may decrease healthcare-associated infections. The purpose of this study is to evaluate the effect of daily bathing with disposable chlorhexidine-impregnated bathing cloths, as compared to daily bathing with disposable standard non-chlorhexidine-impregnated bathing cloths, on the rates of healthcare-associated infections in critically-ill patients. Hypothesis: Daily bathing of the skin with chlorhexidine-impregnated bathing cloths will result in reduced rates of healthcare-associated infections in patients admitted to intensive care units (ICU).

NCT ID: NCT02032732 Terminated - Septic Arthritis Clinical Trials

Utilization of Leukocyte Esterase in the Diagnosis of Pediatric Joint Infections

Start date: December 2013
Phase:
Study type: Observational

Pediatric joint infections are a common diagnostic dilemma encountered by treating orthopaedic surgeons. No single test is sensitive or specific enough to stand alone in determining the presence of joint infection. The purpose of this study is to test the usefulness of a chemical test strip to detect infection in fluid that is removed from a joint (intra-articular aspiration) in pediatric patients. The test strip measures an enzyme called leukocyte esterase, which has been shown to be useful in detecting the presence of infection in fluids from other parts of the body. This study will assess the efficacy of the leukocyte esterase test as a diagnostic tool for evaluating pediatric joint infections. The hypothesis of the study is that a positive leukocyte esterase test identifies a septic joint in pediatric patients undergoing intraoperative joint aspiration.

NCT ID: NCT02032394 Recruiting - Clinical trials for Urinary Tract Infection

Effect of Chlorhexidine on Bacteriuria

Start date: July 2013
Phase: Phase 4
Study type: Interventional

This study is conducted to determine and compare the effect of applying Povidone-iodine and Chlorhexidine solutions for perinea washing on bacteriuria rate and type in patients with urinary catheter in intensive care unit.

NCT ID: NCT02032056 Terminated - Allergy Clinical Trials

Effect of Probiotics in Reducing Infections and Allergies in Young Children During the Complementary Feeding Period

ProbiComp
Start date: September 2013
Phase: N/A
Study type: Interventional

The aim of the intervention is to examine the effect of the bacterial strain BB-12, provided for 6 mo, on the prevalence of infections and allergic manifestations in small children, and how BB-12 affects the immune system, the gastrointestinal tract and the microbiota. Children are enrolled during 2 winter seasons.