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Infection clinical trials

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NCT ID: NCT00690378 Completed - Clinical trials for Complicated Urinary Tract Infection

Comparative Study of NXL104/Ceftazidime Versus Comparator in Adults With Complicated Urinary Tract Infections

Start date: November 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether NXL104 plus ceftazidime is effective in the treatment of complicated urinary tract infections as compared to a comparator group.

NCT ID: NCT00689741 Completed - Clinical trials for Infections, Papillomavirus

Efficacy Study of HPV-16/18 Vaccine (GSK 580299) to Prevent HPV-16 and/or -18 Cervical Infection in Young Healthy Women

Start date: January 2001
Phase: Phase 2
Study type: Interventional

The purpose of this phase IIB MedImmune-sponsored study was to evaluate the efficacy of the HPV-16/18 VLP vaccine in the prevention of infection with HPV-16 and/or HPV-18 in adolescent and young adult women. A vaccine that prevents, or even reduces, the incidence of the common types of high-risk HPVs, particularly HPV-16 and HPV-18, could result in significant reduction in the incidence of cervical cancer and cancer-related mortality, as well as a reduction in the incidence of surgical procedures following abnormal Pap smears.

NCT ID: NCT00688610 Completed - Clinical trials for Respiratory Tract Infection

Antibiotics in Patients With Acute Respiratory Tract Infection With Procalcitonin as Parameter

Start date: November 2007
Phase: Phase 2
Study type: Interventional

Antibiotics in patients with acute respiratory tract infections in primary care in consideration of procalcitonin as additive parameter. The purpose of this study is to compare the ordinary manner of antibiotic- prescription with the prescription in consideration of procalcitonin-value in patients with acute respiratory tract infections.

NCT ID: NCT00685867 Completed - MRSA Infection Clinical Trials

Two Strategies for Methicillin-resistant Staphylococcus Aureus (MRSA) Infection Prevention in Surgical Patients

MOSAR-04
Start date: May 2008
Phase: N/A
Study type: Interventional

The study is a two-arm controlled multi-centre trial of two strategies to reduce nosocomial MRSA transmission and infection among surgical patients. Enrolment and primary analyses will be performed at the hospital level. A total of ten adult surgical departments with at least 3 surgical subspecialties each will participate in the study. Sites of the study are located in 9 countries (UK, France, Spain, Germany, Switzerland, Italy, Serbia, Greece and Israel). The primary objective is to determine the effect of an early MRSA detection & decolonization & isolation strategy compared to an enhanced standard control strategy on healthcare-associated MRSA isolation rates among surgical patients at risk of MRSA carriage, who are hospitalized for at least 24 hours.

NCT ID: NCT00685698 Completed - Clinical trials for Diabetic Foot Infections

Safety and Efficacy Study of TG-873870 (Nemonoxacin) in Diabetic Foot Infections

Start date: June 2008
Phase: Phase 2
Study type: Interventional

Safety and Efficacy Study of TG-873870 (Nemonoxacin) in Diabetic Foot Infections

NCT ID: NCT00683332 Completed - Clinical trials for Complicated Intra-abdominal Infections

Post-Marketing Study Of The Safety Of Tygacil (Tigecycline)

Start date: April 2007
Phase: N/A
Study type: Observational

The purpose of this study is to collect post-marketing information on the safety of Tygacil in Filipino patients.

NCT ID: NCT00679835 Completed - Clinical trials for Gram Positive Infection

PK and Safety Evaluation of Daptomycin in Children Ages 2-6 With Proven or Suspected Gram-positive Infections

Start date: June 3, 2008
Phase: Phase 1
Study type: Interventional

This is a research study designed to look at the pharmacokinetics (distribution, breakdown, and removal) and tolerability of a single dose of daptomycin in patients aged 2 to 6 years who have infections that are caused by a specific group of bacteria (called Gram-positive bacteria).

NCT ID: NCT00679497 Completed - HIV Infections Clinical Trials

A Phase I Study of Modified Vaccinia Virus Ankara (MVA-B) in Healthy Volunteers at Low Risk of HIV Infection

RisVac02
Start date: June 2008
Phase: Phase 1
Study type: Interventional

The purpose of this clinical trial is to study a modified pox viral vector considering: 1. HIV subtype B accounts for the most frequent virus strain in Europe and North America, as well as in many parts of the world. 2. This novel vaccinia construct expressing HIV subtype B gag, pol, env and nef antigens is to be studied in humans for the first time.

NCT ID: NCT00679302 Completed - Clinical trials for Skin Diseases, Infectious

Utility of Trimethoprim-sulfamethoxazole Use in Skin Abscess Management

Start date: July 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if antibiotics are required in the management of skin abscess following incision and drainage.

NCT ID: NCT00678106 Completed - Clinical trials for Bacterial Infections

Study Of Dalbavancin Drug Levels Achieved In Hospitalized Adolescents Who Are Receiving Antibiotic Therapy For Bacterial Infections

Start date: September 2008
Phase: Phase 1
Study type: Interventional

Adolescent subjects hospitalized for the treatment of bacterial infections will be given 1 gram of dalbavancin through their veins and levels of dalbavancin in blood and urine will be measured at different time points. Safety labs will also be checked on a regular basis to assess the safety of dalbavancin.