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Infection clinical trials

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NCT ID: NCT03222804 Withdrawn - Clinical trials for Microbial Colonization

Milk Oriented Microbiota

MOM
Start date: May 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if supplementing healthy term infants delivered vaginally who consume breast milk, formula, or both with a probiotic for 21 consecutive days increases levels of bacteria in infants' stool.

NCT ID: NCT03222583 Completed - Clinical trials for Hepatitis C Virus (HCV)

A Study to Evaluate the Efficacy and Safety of Glecaprevir/Pibrentasvir (ABT-493/ABT-530) in Treatment-Naive and Treatment-Experienced, Non-Cirrhotic Asian Adults With Chronic Hepatitis C Virus Genotype (GT) 1 to GT6 Infection With or Without Human Immunodeficiency Virus Co-Infection

VOYAGE-1
Start date: October 4, 2017
Phase: Phase 3
Study type: Interventional

This study will evaluate the efficacy and safety of glecaprevir/pibrentasvir (ABT-493/ABT-530) in non-cirrhotic chronic hepatitis C virus (HCV) genotype (GT)1 to GT6-infected Asian participants with or without human immunodeficiency virus (HIV) co-infection who are HCV treatment-naïve or treatment-experienced with interferon (IFN) with or without ribavirin (RBV), OR sofosbuvir with RBV with or without IFN.

NCT ID: NCT03222232 Completed - Intestinal Failure Clinical Trials

Catheter Salvage in Intestinal Failure Patients

Start date: January 1, 2002
Phase: N/A
Study type: Observational

This is an observational study evaluating a catheter salvage strategy in relation to catheter-related bloodstream infections in patients with chronic intestinal failure dependent on home parenteral support. The study is confined to the period 2002 to 2016.

NCT ID: NCT03221504 Recruiting - Clinical trials for Urinary Tract Infections in Children

7-day Compared With 10-day Antibiotic Treatment for Febrile Urinary Tract Infections in Children

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The investigators aim to assess the effectiveness of a 7-day compared with a 10-day course of antibiotic treatment for febrile urinary tract infections (UTIs) in children. It is formulated a hypothesis that a 7-day course of antibiotic therapy is equally effective as a 10-day course of therapy and would entail a lower risk of adverse events and better compliance.

NCT ID: NCT03221127 Active, not recruiting - Depression Clinical Trials

Kuopio Ischaemic Heart Disease Risk Factor Study (Nutrition Component)

Start date: March 1, 1984
Phase:
Study type: Observational

To determine associations between dietary factors and risk of major chronic diseases and their risk factors

NCT ID: NCT03218696 Not yet recruiting - Cough Clinical Trials

Comparison of a Protective Cough Syrup Against Placebo on Night Cough in Children 1-5 Years Coughing Since 1- 2 Days Due to Common Cold

Start date: February 2018
Phase: N/A
Study type: Interventional

The intent of this study is to see how boys and girls aged 1-5 and coughing since 1-2 days due to common cold respond to a specific protective cough syrup taken before going to bed for one night, with respect to a similar but not specific syrup (placebo). The symptoms evaluated include especially cough frequency but also cough intensity, bother, and sleep quality of the child and parents.

NCT ID: NCT03217552 Recruiting - Sepsis Clinical Trials

The Performance of the Mologic Biomarker Panel in Infection

Start date: November 26, 2017
Phase:
Study type: Observational

This study is a prospective, single center, observational, cohort study of patients to determine whether the Mologic Biomarker Panel can identify patients with infection from those without, including those with other reasons for inflammation (e.g. post-operative). It will also assess whether it has the potential to judge the severity of illness, prognosticate outcome and guide antibiotic therapy. The aim is to recruit patients who are "representative" of patients with suspected sepsis, uncomplicated infection, or non-infection related critical illness that require critical care intervention and assessment. This study is observational and will not alter patient management or the standard of care. The results from the investigational Mologic Biomarker Panel and associated research assays will not be provided to treating clinicians, or used in any manner to affect patient care. The study will take place over approximately an 18-month period and it is anticipated that approximately 600 patients will be collectively enrolled. The study aims to recruit patients from three environments within UCLH: - The Emergency Department. - Critical Care Unit - Patients undergoing major surgery

NCT ID: NCT03214822 Completed - Oxidative Stress Clinical Trials

Human-derived Human Milk Fortifiers (H2MF), Gut Microbiota and Oxidative Stress in Premature Infants

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

This is a randomized controlled trial of a human-derived human milk fortifier (H2MF) vs standard bovine-derived human milk fortifier (HMF) evaluating fecal microbiota and fecal and urinary biomarkers of oxidative stress in premature infants.

NCT ID: NCT03212729 Completed - Infection Clinical Trials

Antimicrobial Photodynamic Therapy Associated With the Conventional Endodontic Treatment: A Clinical and Microbiological Study

Start date: April 2015
Phase: N/A
Study type: Interventional

Microorganisms play a critical role in the etiology and pathogenesis of apical periodontitis. Enterococcus faecalis and Candida sp. are frequently associated with persistent infections. The aim of this study was evaluated the antimicrobial photodynamic therapy (aPDT) as an adjunct of the endodontic treatment. Ten uniradicular teeth [control group (CG)=4 and test group (TG)=6] with primary endodontic infections were analyzed. Microbiological samples were collected before and after the chemical-mechanical instrumentation (CMI), after the aPDT (for the TG) and after the temporary restorations removal (second session).

NCT ID: NCT03211026 Recruiting - Clinical trials for Kidney Transplantation

Urinary Tract Infections in Kidney Transplant Recipients

URIKIT
Start date: May 4, 2017
Phase:
Study type: Observational

The purpose of this study is to better estimate the prevalence of urinary tract infections (UTI) in kidney transplant (KIT) recipients, and especially multidrug resistant (MDR) bacteria. KIT recipients have a higher risk of UTI over the 6 first months following the transplantation. Urine culture was done in a city lab or at hospital. Current data on bacteriuria and candiduria lead mostly to hospital data that are incomplete..