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IBS - Irritable Bowel Syndrome clinical trials

View clinical trials related to IBS - Irritable Bowel Syndrome.

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NCT ID: NCT05016596 Completed - Clinical trials for IBS - Irritable Bowel Syndrome

Postprandial Lipids in IBS and Nutritional Treatment

PLINT
Start date: November 15, 2021
Phase: N/A
Study type: Interventional

Irritable Bowel Syndrome (IBS) is a disease that affects a large number of people. Adequate treatment is difficult, partially due to the heterogeneity of the patients and the complicated pathology in which not all mechanisms are understood. Based on literature and in vitro screening within the public private IBSQUtrition consortium project, a turmeric supplement was selected for in vivo validation of its potential beneficial effects on fat-induced intestinal barrier disruption as measured with LPS translocation in IBS patients with a diarrhea-predominant subtype (IBS-D). The primary objective of this study is to determine the effect of turmeric supplementation on LPS translocation in IBS-D patients after a high-fat challenge. The secondary objective of this study is to determine the effect of turmeric supplementation on gastrointestinal complaints and LPS-related biomarkers in IBS-D patients after a high-fat challenge. In this double-blind, randomized, placebo-controlled cross-over trial 20 adult (18-70 yrs) IBS-D patients will be included. Study participants have to invest about 16 hours of their time in this study. They will visit the research facility three times. The risks for participation are very small if not negligible. Consumption of high amounts of saturated fat may cause some gastro-intestinal discomfort. Blood sampling will be performed via a cannula and the insertion can be a bit painful and may cause a bruise. The amount of blood that is drawn from participants is relatively small and within acceptable limits.

NCT ID: NCT04946604 Completed - Clinical trials for IBS - Irritable Bowel Syndrome

Ashtangayoga for IBS Show Positive Preliminary Effects on Symptoms and Well-being

Start date: January 18, 2018
Phase: N/A
Study type: Interventional

The study aims to test the effect of Ashtanga yoga on well-being in patients with irritable bowel syndrome (IBS). The intervention comprises group sessions on the Ashtanga school of yoga. Participants are recruited from primary care and measurements on well-being and IBS symptoms are conducted at pre-treatment, post-treatment and 6-month follow-up.

NCT ID: NCT04905524 Completed - Depression, Anxiety Clinical Trials

Activity Changes in Irritable Bowel Syndrome (IBS), Anxiety, and Depression Following the Use of Viome Precision Nutrition Program (VPNP)

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

Viome costumers are consented and recruited for this study and complete the questionnaires upon enrollment. Any participant who previously self reported depression, anxiety, or Irritable Bowel Syndrome (IBS) qualify for this study. All participants receive Viome's diet, supplement and recommendations.

NCT ID: NCT04898257 Completed - Clinical trials for IBS - Irritable Bowel Syndrome

Effect of Lactibiane Tolerance® to Treat Leaky Gut in Irritable Bowel Syndrome With Predominant Diarrhea (IBS-D)Patients

Start date: May 17, 2018
Phase: N/A
Study type: Interventional

This is a Phase IV, open-label, single-center, proof-of-concept, pilot study to evaluate the effect of Lactibiane Tolerance® in treating leaky gut in IBS-D patients. 30 consecutive patients with IBS-D and an increased intestinal permeability assessed by 51Cr-EDTA or 99mTc-DTPA will receive the multistrain probiotic Lactibiane Tolerance® 10 billion CFU 1 capsule twice a day (30 minutes before breakfast and 30 minutes before dinner) for 30 days treatment. At the end of treatment, patients will repeat intestinal permeability assessment by 51Cr-EDTA or 99mTc-DTPA.

NCT ID: NCT04817683 Completed - Clinical trials for IBS - Irritable Bowel Syndrome

Study on the Relationship Between Mobile Phone Addiction and Functional Gastrointestinal Disorders

Start date: July 1, 2020
Phase:
Study type: Observational

A cross-sectional study was conducted to collect the relevant data of college students' mobile phone addiction and FGIDs (IBS, FD) in the form of questionnaire, so as to understand the situation of college students' mobile phone addiction and the incidence of FGIDs (IBS and FD), and explore the correlation, so as to provide new ideas and scientific basis for the prevention, diagnosis and treatment of FGIDs among college students.

NCT ID: NCT04760353 Recruiting - Obesity Clinical Trials

The Effect of a Probiotic Mixture in Obese Patients With Irritable Bowel Syndrome

Start date: November 10, 2021
Phase: N/A
Study type: Interventional

The objective of the current study is to evaluate the effect of a probiotic mixture on the adequate relief and faecal microbiota in obese patients with irritable bowel syndrome

NCT ID: NCT04723056 Active, not recruiting - Clinical trials for IBS - Irritable Bowel Syndrome

Zemedy Application for Irritable Bowel Syndrome

Start date: October 15, 2021
Phase: N/A
Study type: Interventional

The purpose of the study is investigate the effectiveness of Zemedy, a mobile application that enables the digital delivery of a CBT program to people with IBS.

NCT ID: NCT04543474 Completed - Clinical trials for IBS - Irritable Bowel Syndrome

Treatment Efficacy of Low FODMAP Versus Low Lactose Diet in IBS Patients

Start date: March 11, 2015
Phase: N/A
Study type: Interventional

A low FODMAP diet (LFD) has become a standard treatment in irritable bowel syndrome (IBS) patients. Compliant adherence to a LFD is challenging. The investigator looked at the effect of a LFD compared to a less restrictive low lactose diet (LLD) in a randomized cross-over trial with IBS patients.

NCT ID: NCT04422327 Completed - Depression, Anxiety Clinical Trials

The Impact of a Combination of Bifidobacterium Longum 35624® and 1714™ Strains in Adults With Irritable Bowel Syndrome

IBS
Start date: September 20, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

This study aimed to assess the impact of consumption of COMBO, a combination product of two Bifidobacterium longum strains, on stress, mood and bowel symptoms in adults with Irritable Bowel Syndrome (IBS).

NCT ID: NCT04348760 Completed - Inflammation Clinical Trials

Study of Inflammatory Markers and Symptom Severity in Personalized Nutritional Intervention in IBS

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

Irritable Bowel Syndrome (IBS) is a widespread disease with variable symptoms that have an important impact on the quality of life. Despite the prevalence of IBS, its etiology and pathophysiology are still to be fully understood, but immune response is known to be involved. In this study, the investigators researched the variation of two specific cytokines, B-cell activating factor (BAFF) and platelet-activating factor (PAF), the levels of food-specific IgG and the symptom severity, using Irritable Bowel Syndrome - Symptom Severity Score (IBS-SSS), following a personalized an unrestricted-calorie diet.