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Hypoglycemia clinical trials

View clinical trials related to Hypoglycemia.

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NCT ID: NCT06404528 Recruiting - Solid Tumors, Adult Clinical Trials

Low-dose Chemotherapy Under Hypoglycaemia for the Treatment of Relapsed Refractory Advanced Solid Tumours

Start date: September 4, 2023
Phase: N/A
Study type: Interventional

By controlling the patient's blood sugar, small doses of chemotherapy are used in a hypoglycemic state. Some necrotic tumor cells produced by chemotherapy can maintain their immunogenicity, further activate innate immunity, and produce very strong anticancer effects without the cytotoxic effects of chemotherapy.

NCT ID: NCT06384118 Completed - Clinical trials for Type 2 Diabetes Mellitus

Effects of a Health Intervention on Hypoglycemic Coping : a Pilot Study

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

From August 2023 to January 2024, 100 patients with type 2 diabetes who met the inclusion and exclusion criteria were selected from the endocrinology department of The purpose of this study was to construct a hypoglycemia coping intervention program for type 2 diabetic patients based on the IMB theory and to investigate the feasibility, acceptability, and initial effects of the program.

NCT ID: NCT06382350 Not yet recruiting - Clinical trials for Type 1 Diabetes Mellitus

Glycemic Excursions in Patients With Type 1 Diabetes Mellitus Using Closed-loop Systems

SAFEDRIVE
Start date: April 2024
Phase:
Study type: Observational

The study aims to compare glycemic excursions during several life situations (such as periods of driving, periods of night sleep, periods of occupation, periods of physical activity, and periods of stress) in patients with type 1 diabetes treated with closed-loop system and multiple daily insulin dose therapy

NCT ID: NCT06373432 Not yet recruiting - Clinical trials for Neonatal Hypoglycemia

Frequency of Glucose Monitoring in Labor

Start date: April 2024
Phase: N/A
Study type: Interventional

The aim of this study is to assess rates of neonatal hypoglycemia with differing intrapartum glucose protocols. Currently at this time there is no guidance from professional medical organizations about when and how frequent to assess maternal glucose levels intrapartum. Several institutions have no protocols in place. The study will be a randomized controlled trial placing patients with Gestational Diabetes Mellitus (GDM) in "frequent" vs "infrequent" glucose monitoring intrapartum and assessing neonatal glucose levels at birth.

NCT ID: NCT06363929 Recruiting - Hyperinsulinism Clinical Trials

Continuous Glucose Monitoring in Neonatal Hyperinsulinism

Start date: June 1, 2023
Phase:
Study type: Observational

The investigators are studying the accuracy of Dexcom G6 continuous glucose monitors placed on babies with hyperinsulinism in the Miller Children's Hospital Neonatal Intensive Care Unit. The participants will wear the device for 10 days on their lateral thigh. Whenever blood sugars are checked by glucometer, the investigators will also record the continuous glucose monitor sugar. Additionally, if the continuous glucose monitor alarms for a low sugar or an impending low sugar, the investigators will check the blood sugar by glucometer and, if verified to be low, treat the low blood sugar accordingly.

NCT ID: NCT06353217 Recruiting - Diabetes Mellitus Clinical Trials

Study of a Primary Care Hypoglycemia Prevention Program

Start date: April 14, 2024
Phase: N/A
Study type: Interventional

This is a single site, pre-post pilot study. The objective is to evaluate the acceptability and feasibility of a primary care hypoglycemia prevention program for patients taking hypoglycemia-causing medications. The study will also evaluate relevant process outcomes and clinical outcomes for refining the intervention and planning for a larger efficacy trial.

NCT ID: NCT06325202 Not yet recruiting - Clinical trials for Diabetes Mellitus, Type 1

Closed Loop and Education for Hypoglycemia Awareness Restoration

CLEAR
Start date: July 1, 2024
Phase: N/A
Study type: Interventional

The purpose of the CLEAR study is to determine the effect on counterregulatory responses (CRR) of intervening (by attempting to strictly avoid hypoglycemia) to improve awareness of hypoglycemic symptoms among adults with type 1 diabetes (T1D) who have impaired awareness of hypoglycemia (IAH). IAH affects 20-25% of adults with T1D, and rises with increasing duration of T1D.

NCT ID: NCT06320730 Completed - Acute Kidney Injury Clinical Trials

Impact of Glycemic Control After Reperfusion on Acute Kidney Injury in Living Donor Liver Transplantation

Start date: August 25, 2020
Phase:
Study type: Observational

This retrospective cohort study of patients classified by the blood glucose level after reperfusion in liver transplantation repicient. Our object is to investigate whether controlling BG levels within the optimal range during neohepatic phase is associated with a reduction of AKI incidence. Furthermore, severe AKI, chronic kidney disease (CKD), major adverse cardiac event (MACE) and mortality were also investigated.

NCT ID: NCT06297980 Recruiting - Type 1 Diabetes Clinical Trials

Impact of MEnstruation on Glycemic Response and Exercise In Females With Type 1 Diabetes

MERIT
Start date: March 15, 2024
Phase: N/A
Study type: Interventional

The objectives of this study are to examine how sex hormones (use of hormonal birth control, menstrual cycle phase) impact glycemic control among women with type 1 diabetes (T1D), and to test adjustments to insulin dosing and food intake to ameliorate cycle-related glycemic variability. A secondary aim is to examine how the menstrual cycle and use of hormonal birth control impact patient-reported outcomes and glycemic responses to physical activity.

NCT ID: NCT06296485 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

Safer Aging With Diabetes Monitoring

SAGE
Start date: May 1, 2024
Phase: N/A
Study type: Interventional

Older adults with type 2 diabetes are at higher risk for severe hypoglycemia and its related complications (including hospitalization and death) when taking insulin. This study proposes to evaluate, in a randomized clinical trial, a strategy of safe insulin prescribing based on an educational program that leverages continuous glucose monitoring to support older adults at high risk for hypoglycemia. If the aims of this project are achieved, this novel care strategy could be widely applied to reduce severe hypoglycemia episodes in older, high-risk adults with type 2 diabetes.