Hypertension Clinical Trial
Official title:
Self-Management and Resilience Trajectories in African American Adults With Hypertension
Verified date | June 2024 |
Source | Case Western Reserve University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Hypertension (HTN) rates have increased worldwide, but the most significant increase in the incidence of morbidity and mortality has been in African Americans (AA)1,2 (43% vs 27% for other U.S. population groups). Despite evidence of positive benefits from lifestyle modification (healthy diet, reduced sodium intake, increased physical activity, smoking cessation) and prescribed antihypertensive therapy (AHT) many AA with HTN do not adhere to their treatment regimens. Consistent, effective lifelong self-management is required to sustain optimal BP control and thus reduce morbidity and mortality. Self-managing HTN to a blood pressure (BP) <130/80 mm Hg presents challenges such as juggling multiple medications and health care providers, dealing with complex recommendations and treatment regimens, and coping with negative emotional states. Few studies have examined the biopsychosocial mechanisms that foster effective HTN self-management and resilience among AA living with HTN. Understanding the mechanisms that influence HTN self-management and resilience in AA holds the promise of new modifiable targets for behavior-change interventions. This study explores the relationship among resilience precursors on hypertension (HTN) self-management behaviors, stress response, and the effects that these relationships have on health outcomes-health-related quality of life (HRQOL) and blood pressure (BP) in African Americans (AA) with HTN over a 6-month period.
Status | Active, not recruiting |
Enrollment | 125 |
Est. completion date | November 30, 2024 |
Est. primary completion date | November 30, 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 25 Years and older |
Eligibility | Inclusion Criteria: - Self-identify as African American - 25 years of age or older - Diagnosed with hypertension and prescribed one antihypertensive medication - BP >130/80 mmHg - Have at least one additional chronic health conditions - Able to read/understand English Exclusion Criteria: - Unable to give informed consent or judged to have impaired cognitive ability or severe memory - Have experienced a major CVD event or procedure (e.g., myocardial infarction, stroke, heart surgery) within the past year |
Country | Name | City | State |
---|---|---|---|
United States | University Hospitals Cleveland Medical Center | Cleveland | Ohio |
Lead Sponsor | Collaborator |
---|---|
Case Western Reserve University | University Hospitals Cleveland Medical Center |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | systolic and diastolic Blood Pressure | Measure of participants' in clinic blood pressure (average of three blood pressure readings). | Baseline - 6 months | |
Primary | PROMIS Global Health-10 [health-related quality of life] | Total summed score on PROMIS Global Health-10 that range from 4-20.Higher scores indicate greater health-related quality of life. | Baseline - 6 months |
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