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Clinical Trial Summary

Obesity and type 2 diabetes mellitus (T2DM) are reaching epidemic proportions in the developed world. In morbidly obese patients only surgical treatment (bariatric operations) leads to a sustained weight loss and relief of co-morbidities in the majority of patients. One of the most frequently performed operations is the laparoscopic proximal Roux-en-Y gastric bypass (LRYGB). There is still lack of knowledge why some patients respond much better than others to an identically performed procedure. Therefore, a number of variations of this operation have been introduced over the past 50 years. Increasing the length of small bowel being bypassed has the potential to improve the effect of the operation but buries the risk of nutrient deficiencies. The metabolic effect of LRYGB occurs, in part, independently of weight loss. The mechanisms underlying metabolic improvement through metabolic surgery are not yet fully understood.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04219787
Study type Interventional
Source Clarunis - Universitäres Bauchzentrum Basel
Contact
Status Active, not recruiting
Phase N/A
Start date June 1, 2020
Completion date November 30, 2028

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