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Comparison of Tandospirone, Amlodipine and Their Combination in Adults With Hypertension and Anxiety

Hypertension Clinical Trial

Official title:
Comparison of Tandospirone, Amlodipine and Their Combination in Adults With Hypertension and Anxiety: a Multicentre, Randomized, Double-blind, Double-dummy, Placebo-controlled Trial

Clinical Trial Summary

This study compares the antihypertensive effects between different treatment groups including antihypertensive drug, anxiolytic, and both, which provide a new clinical evidence for controlling blood pressure in patients with hypertension and anxiety.

Clinical Trial Description

In recent years, many studies have found that elevated blood pressure is associated with anxiety. It has been report that the incidence of hypertension with anxiety is 25%-54%. The studies have confirmed that anxiety can significantly reduce the antihypertensive effect. Therefore, anxiolytics can increase the antihypertensive effect in patients with hypertension and anxiety. However, there is currently no standard treatment for patients with hypertension and anxiety, and few clinical studies have focused on the treatment of these neglected patients. Improvement on hypertension through relieving anxiety and relief of anxiety through lowering hypertension are lack of clinical studies to prove. This study compares the antihypertensive effects between different treatment groups including antihypertensive drug, anxiolytic, and both, which provide a new clinical evidence for controlling blood pressure in patients with hypertension and anxiety. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03667677
Study type Interventional
Source Chongqing Medical University
Contact Peng Xie
Phone 86-023-68485490
Email xiepeng@cqmu.edu.cn
Status Not yet recruiting
Phase Phase 4
Start date February 1, 2019
Completion date July 1, 2020
View Details
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