Hypertension Clinical Trial
Official title:
The Depression/Hypertension in Chinese Older Adults-Collaboration in Health
This study will see if education of village doctors and aging workers in identification and management of hypertension and depression, using standardized procedures,consultation with a psychiatrist as needed, and collaborations between the village doctor and aging worker in care elderly patients in the village better achieve better outcomes for their depression and high blood pressure than usual care.
The Depression/Hypertension in Chinese Older Adults - Collaborations in Health (COACH) Study
is a randomized controlled trial (RCT) comparing the COACH intervention to care as usual
(CAU) for the treatment of comorbid depression and hypertension (HTN) in Chinese older adult
rural village residents. COACH integrates the care provided by the older person's primary
care provider (PCP) with that delivered by an Aging Worker (AW; a lay member of the village's
Aging Association), supervised by a psychiatrist consultant. Based on chronic disease
management principles, the PCP is trained to use evidence based practice guidelines for
treatment of both HTN and depression, and provided with access to mental health consultation
regarding optimal management of the patient's depression. The AW is trained to conduct a
systematic assessment of the older person's social context to identify and reduce social and
environmental barriers to treatment adherence and response. AWs participate with the PCP in
developing multidisciplinary care plans for their shared patients, reinforce treatment
adherence and adoption of healthy behaviors, and emphasize activation and engagement of the
older person in activities designed to improve their connectedness to others and to the
community. Finally, PCP, AW, and Psychiatrist Consultant are trained to collaborate in their
shared clients' care.
One hundred and sixty villages will be randomized to deliver COACH or CAU to eligible
subjects who reside there (approximately 15 per village will meet criteria), or a total of
about 2400 subjects. Treatment will continue for one year, with research evaluations at
baseline, 3 6, 9, and 12 months.
Specific aims of the study are to determine whether COACH is more effective than CAU in
treating depression (Aim 1) and HTN (Aim 2); whether improvements in treatment adherence
precede reductions in depression and improvement in BP control (Aim 3a), and whether
improvements in depression symptoms precede improvements in BP control (Aim 3b); if COACH is
associated with greater improvements in health related quality of life than CAU (Aim 4); and
to compare the costs associated with each approach (Aim 5).
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT04591808 -
Efficacy and Safety of Atorvastatin + Perindopril Fixed-Dose Combination S05167 in Adult Patients With Arterial Hypertension and Dyslipidemia
|
Phase 3 | |
| Recruiting |
NCT04515303 -
Digital Intervention Participation in DASH
|
||
| Completed |
NCT05433233 -
Effects of Lifestyle Walking on Blood Pressure in Older Adults With Hypertension
|
N/A | |
| Completed |
NCT05491642 -
A Study in Male and Female Participants (After Menopause) With Mild to Moderate High Blood Pressure to Learn How Safe the Study Treatment BAY3283142 is, How it Affects the Body and How it Moves Into, Through and Out of the Body After Taking Single and Multiple Doses
|
Phase 1 | |
| Completed |
NCT03093532 -
A Hypertension Emergency Department Intervention Aimed at Decreasing Disparities
|
N/A | |
| Completed |
NCT04507867 -
Effect of a NSS to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III
|
N/A | |
| Completed |
NCT05529147 -
The Effects of Medication Induced Blood Pressure Reduction on Cerebral Hemodynamics in Hypertensive Frail Elderly
|
||
| Recruiting |
NCT06363097 -
Urinary Uromodulin, Dietary Sodium Intake and Ambulatory Blood Pressure in Patients With Chronic Kidney Disease
|
||
| Recruiting |
NCT05976230 -
Special Drug Use Surveillance of Entresto Tablets (Hypertension)
|
||
| Completed |
NCT06008015 -
A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1015" and Co-administration of "BR1015-1" and "BR1015-2" Under Fed Conditions in Healthy Volunteers
|
Phase 1 | |
| Completed |
NCT05387174 -
Nursing Intervention in Two Risk Factors of the Metabolic Syndrome and Quality of Life in the Climacteric Period
|
N/A | |
| Completed |
NCT04082585 -
Total Health Improvement Program Research Project
|
||
| Recruiting |
NCT05121337 -
Groceries for Black Residents of Boston to Stop Hypertension Among Adults Without Treated Hypertension
|
N/A | |
| Withdrawn |
NCT04922424 -
Mechanisms and Interventions to Address Cardiovascular Risk of Gender-affirming Hormone Therapy in Trans Men
|
Phase 1 | |
| Active, not recruiting |
NCT05062161 -
Sleep Duration and Blood Pressure During Sleep
|
N/A | |
| Not yet recruiting |
NCT05038774 -
Educational Intervention for Hypertension Management
|
N/A | |
| Completed |
NCT05087290 -
LOnger-term Effects of COVID-19 INfection on Blood Vessels And Blood pRessure (LOCHINVAR)
|
||
| Completed |
NCT05621694 -
Exploring Oxytocin Response to Meditative Movement
|
N/A | |
| Completed |
NCT05688917 -
Green Coffee Effect on Metabolic Syndrome
|
N/A | |
| Recruiting |
NCT05575453 -
OPTIMA-BP: Empowering PaTients in MAnaging Blood Pressure
|
N/A |