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Clinical Trial Summary

This trial will evaluate whether a particular type of circulating white blood cell, monocytes, from type 2 diabetics with high blood pressure and vitamin D deficiency vs. sufficiency will induce hormones that increase blood pressure.


Clinical Trial Description

More than half of patients with type 2 diabetes mellitus develop hypertension, which doubles their risk for cardiovascular disease. Inflammation plays a role in the development of these diseases, and monocytes, a type of white blood cell, may be critical. This study will isolate monocytes from blood samples of patients with type 2 diabetes and high blood pressure who have either high levels of vitamin D or low levels of vitamin D, and determine what their effects are on stimulating production in kidney cells of a hormone that increases blood pressure. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03348280
Study type Observational
Source Washington University School of Medicine
Contact Veronica Worth, MD
Phone 3143620934
Email cbernal@wustl.edu
Status Recruiting
Phase N/A
Start date September 1, 2017
Completion date December 31, 2020

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