Wind Instruments' Fungal Contamination

Hypersensitivity Pneumonitis Clinical Trial

Official title:

Study of Wind Reed Instruments' Fungal Contamination and Its Immunological and Clinical Consequences for Musicians.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01487850
• Other study ID #: P/2007/55
• Status: Completed
• Phase: N/A
• First received: December 6, 2011
• Last updated: December 8, 2011
• Start date: May 2007
• Est. completion date: October 2007

Study information

• Verified date: December 2011
• Source: Centre Hospitalier Universitaire de Besancon
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Délégation à la Recherche Clinique et à l'Innovation
• Study type: Interventional

Clinical Trial Summary

On the basis of 2 cases of immunologically-induced lung disease in 2 saxophonists, the investigators supposed that wind reed instruments could be contaminated with molds. The investigators led a study on 40 musicians playing a wind reed instrument to analyze instruments' fungal contamination and its immunological and clinical consequences for musicians.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 0
• Est. completion date: October 2007
• Est. primary completion date: June 2007
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• must be 18 year old or more

• must play a wind reed instrument (saxophone, clarinet, bassoon or oboe) one hour per week or more

Exclusion Criteria:

• refuse to sign consent

Study Design

Primary Purpose: Diagnostic

Related Conditions & MeSH terms

• Alveolitis, Extrinsic Allergic
• Hypersensitivity
• Hypersensitivity Pneumonitis
• Immunologically-induced Lung Disease
• Lung Diseases
• Pneumonia

Intervention

Biological:
• blood sample
blood sample in each musician to search for specific antibodies against molds isolated from instruments

Locations

Country	Name	City	State
France	Centre Hospitalier Universitaire Saint Jacques	Besancon	Franche Comté

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire de Besancon

Country where clinical trial is conducted

France, 

References & Publications (2)

Lodha S, Sharma OP. Hypersensitivity pneumonitis in a saxophone player. Chest. 1988 Jun;93(6):1322. — View Citation

Metzger F, Haccuria A, Reboux G, Nolard N, Dalphin JC, De Vuyst P. Hypersensitivity pneumonitis due to molds in a saxophone player. Chest. 2010 Sep;138(3):724-6. doi: 10.1378/chest.09-2991. — View Citation