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A Prognostic Transcriptomic Signature for Chronic Hypersensitivity Pneumonitis — PREDICT-HP  

Hypersensitivity Pneumonitis Clinical Trial

Official title:
Development and Validation of a Prognostic Transcriptomic Signature for Chronic Hypersensitivity Pneumonitis

Clinical Trial Summary

Up to 135 patients with hypersensitivity pneumonitis will be enrolled at 7 clinical centers across the United States. Patients will be followed for 24 months to determine if biomarkers in the blood can predict disease progression.

Clinical Trial Description

Hypersensitivity pneumonitis is an immunologically mediated form of lung disease, resulting from inhalation exposure to a large variety of antigens. For unknown reasons, a subgroup of patients with HP without a known inciting antigen exposure develops chronic disease with progressive pulmonary fibrosis (the leading cause of death). Accurately identifying patients at risk of disease progression is necessary for prognosis and therapy. Enrolled subjects will be followed for 24 months and complete 5 visits to one of the study centers. Blood biomarkers will be collected in addition to other clinical data to determine if these biomarkers can predict disease progression. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04844359
Study type Observational
Source National Jewish Health
Contact Kaitlin Fier
Phone 303-270-2852
Email fierk@njhealth.org
Status Recruiting
Phase
Start date January 6, 2021
Completion date January 2026
View Details
See also
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