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Hyperplasia clinical trials

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NCT ID: NCT03850457 Recruiting - Clinical trials for Bronchopulmonary Dysplasia

Epidemiological Study for Bronchopulmonary Dysplasia (BPD) in China

Start date: January 1, 2020
Phase:
Study type: Observational

This study will establish a nationwide cohort of very preterm infants in China, to investigate the epidemiological characteristics and short-term outcomes of BPD in different NICUs around the country.

NCT ID: NCT03846700 Recruiting - Clinical trials for Benign Prostatic Hyperplasia (BPH)

Urodynamic Evaluation of Disobstrucitve Power of Aquablation VS Laser Techniques

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

in the last decade, lots of attemps have been done to identify new technologies able to reply the efficacy of gold standard technique for treating BPH, but with a better safety profile. The introduction of laser techniques allowed to reduce complication rates. Among these, considerable importance had Holep and PVP. Aquablation is a recent technique for LUTS treatment. It is minimally invasive, robot-assisted and ultrasound-guided to ablate the prostate in targeted way and in "heat-free" way. It works with high pression water jet. However, in literature informations about disobstructive capacity of minimally invasive techniques, evaluated with invasive urodynamic tests, are low. The enrolled subjects will undergo surgical treatment with one of the techniques under study: Aquablation, HoLEP or PVP. Outpatient visits will be performed at 1, 3 and 6 months after the surgical treatment. During the sixth month visit an invasive urodynamic examination will be performed

NCT ID: NCT03845933 Completed - Clinical trials for Right Colon Hyperplastic Polyp Miss Rate

Right Colon Polyp Miss Rates of Water Exchange and Carbon Dioxide Insufflation Colonoscopy

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

This will be a prospective randomized controlled trial comparing CO2 insufflation and WE in terms of right colon combined adenoma miss rate (AMR) and hyperplastic polyp miss rate (HPMR) by tandem inspection. It will be a single-site study conducted in Taiwan.

NCT ID: NCT03831321 Recruiting - Pain Clinical Trials

The Effect of Preemptive Analgesia On The Comfort Of Patient and Doctor, in Cystoscopy

Start date: December 11, 2018
Phase: Phase 4
Study type: Interventional

The study was designed as a prospective, randomized double-blind placebo controlled trial. According to power analysis in regards of previous studies in the literature with diclofenac sodium, using a total of 144 patients are needed for Power: 80% and Efficacy: 0.05. diclofenac (20 mg) and placebo drugs to be used in the study will be numbered 1 and 2 individually. Patient randomization was performed using random.org in 144 patients. On the day of cystoscopy, the patient randomized according to inclusion criteria will be given a medication package corresponding to the number given in randomization. It will not be known by the staff and cystoscopy will be performed by the physician who does not know which package is an effective drug. Parameters: 1. Visual Pain Score during cystoscopy 2. Cystoscopy comfort - a questionnaire to be filled by the doctor 1. Excellent 2. Very good 3. Good 4. Bad 5. Too bad 3. Cystoscopy: Is it efficient? Not efficient? - Will be answered by the doctor. Post-Op: 1. 1st hour Visual Analog Pain Scale inquiry, dysuria, frequency 2. 24th Hour dysuria, Frequency, A total of 144 patients, we plan to arrive at the end of 1 month.

NCT ID: NCT03829904 Completed - Clinical trials for Benign Prostatic Hyperplasia

The Effect of Traditional Chinese Medicine on Benign Prostatic Hyperplasia

Start date: March 6, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

This randomized, double-blinded, placebo-controlled, crossover clinical trial aims to investigate the effect of VGH-BPH1, a scientific Chinese medicine powder prescription, on patients with benign prostatic hyperplasia.

NCT ID: NCT03817216 Withdrawn - Prostate Cancer Clinical Trials

Prostatic Urethral Lift (PUL) Pre-/Post-Radiation Treatment for Prostate Cancer

Start date: December 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to test the use of the Prostatic Urethral Lift (PUL), Urolift®, in prostate cancer (Pca) participants seeking or undergoing radiotherapy for relief of urinary obstructive symptoms.

NCT ID: NCT03814824 Completed - Clinical trials for Barrett's Esophagus Without Dysplasia

Volumetric Laser Endomicroscopy With Intelligent Real-time Image Segmentation (IRIS)

Start date: January 23, 2019
Phase: N/A
Study type: Interventional

This is a prospective randomized clinical trial examining how IRIS (Intelligent Real-time Image Segmentation) affects biopsy patterns in VLE (Volumetric laser endomicroscopy).

NCT ID: NCT03814629 Active, not recruiting - Clinical trials for Chronic Atrophic Gastritis With Hyperplasia (Diagnosis)

Clinical Study of Weifuchun Treatment on Precancerous Lesions of Gastric Cancer

Start date: August 1, 2015
Phase: Early Phase 1
Study type: Interventional

Research purpose To elucidate the effect mechanism and clinical effective of weifuchun in the prevention and treatment of chronic atrophic gastritis and precancerous lesions of gastric cancer. From genes related to cell differentiation, proliferation, apoptosis, tumor invasion and metastasis, genes related to immune inflammation and immune escape and other possible aspects to elucidate the effective and mechanism of weifuchun's treatment on chronic atrophic gastritis, reversing precancerous lesions of gastric cancer.

NCT ID: NCT03776006 Not yet recruiting - Clinical trials for Lower Urinary Tract Symptoms

Registry: TPLA for LUTS

Start date: February 1, 2019
Phase:
Study type: Observational [Patient Registry]

Rationale: The treatment of lower urinary tract symptoms (LUTS) due to benign prostatic enlargement in men with transperineal laser ablation (TPLA) may offer advantages in functional outcomes and safety over current standard therapies. As the technique is relatively new, indications and outcomes for this treatment are subject of investigation. However, the technique is already applied outside clinical studies. Clinical information from these treatments can be useful for future research. The aim of this study is to collect data on patients treated with transperineal laser ablation of the prostate outside clinical trials and to provide data on safety and functional outcomes in these patients in order to improve treatment. Objective: To assess long-term efficacy of transperineal laser ablation for lower urinary tract symptoms, to assess functional outcomes, to assess safety, to determine baseline patient characteristics, to collect information on possible differences between centres applying treatment of transperineal laser ablation and to explore the optimal treatment indications and possible limitations. Study design: This is an international prospective observational study in which data is recorded of patients who are treated with transperineal laser ablation for lower urinary tract symptoms. Study population: Male patients treated with transperineal laser ablation for lower urinary tract symptoms due to benign prostatic enlargement. Main study parameters/endpoints: The primary endpoint of this study is long-term efficacy of transperineal laser ablation for lower urinary tract symptoms measured by the time until surgical retreatment.

NCT ID: NCT03768765 Recruiting - Clinical trials for Benign Prostatic Hyperplasia

Duration of Medication Therapy and Outcomes After Holmium Laser Prostate Surgery for Patients With Benign Prostatic Hyperplasia (BPH)

Start date: November 15, 2018
Phase:
Study type: Observational

To determine if the prior prolonged use of medication, as a treatment for benign prostatic hyperplasia, reduces the efficacy of Holmium laser enucleation of the prostate (HoLEP) for patients with benign prostatic hyperplasia (BPH).