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Hyperlipidemia clinical trials

View clinical trials related to Hyperlipidemia.

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NCT ID: NCT00376584 Completed - Hyperlipidemia Clinical Trials

Effect of an Investigational Compound on Tolerability of Extended Release Niacin (0524A-023)(COMPLETED)

Start date: July 2006
Phase: Phase 3
Study type: Interventional

This is a 12-week clinical trial in lipid clinic patients for whom niacin therapy is appropriate to evaluate the efficacy of MK0524 to improve the tolerability of extended-release niacin. There will be 6 scheduled clinic visits and 3 treatment arms.

NCT ID: NCT00365742 Completed - Hyperlipidemia Clinical Trials

Statin Therapy Vs. Therapeutic Lifestyle Changes and Supplements

Start date: April 2006
Phase: N/A
Study type: Interventional

Randomized trial in a primary prevention population - all participants have high LDL cholesterol Group one will take simvastatin 40 mg/day Group Two will make therapeutic lifestyle changes,and take supplements consisting of red yeast rice and fish oil

NCT ID: NCT00362934 Completed - Hyperlipidemia Clinical Trials

Comparison of the Combination of Fenofibrate and Simvastatin Versus Atorvastatin

Start date: October 2006
Phase: Phase 3
Study type: Interventional

Mixed or combined hyperlipidemia is a common metabolic disorder characterized by both hypercholesterolemia and hypertriglyceridemia. Statins and fibrates have complementary mechanisms and can be coadministered to patients with mixed hyperlipidemia. The overall objective of the study is to compare the efficacy and safety of combining fenofibrate and simvastatin versus atorvastatin monotherapy in patients with mixed hyperlipidemia at risk of cardiovascular diseases.

NCT ID: NCT00362206 Completed - Hyperlipidemia Clinical Trials

Comparison of the Combination of Fenofibrate and Simvastatin Versus Pravastatin

Start date: September 2006
Phase: Phase 3
Study type: Interventional

Mixed or combined hyperlipidemia is a common metabolic disorder characterized by both hypercholesterolemia and hypertriglyceridemia. Statins and fibrates have complementary mechanisms and can be coadministered to patients with mixed hyperlipidemia.The overall objective of the study is to compare the efficacy and safety of combining fenofibrate and simvastatin versus pravastatin monotherapy in patients with mixed hyperlipidemia at risk of cardiovascular diseases.

NCT ID: NCT00360217 Completed - Clinical trials for Coronary Artery Disease

The Triglyceride Lowering Effect of an Omega-3 Fat (DHA) in Addition to Statin Therapy for Patients With CAD or Diabetes

Start date: January 2006
Phase: N/A
Study type: Interventional

This study will explore the ability of an algae (ocean plant) omega-3 fat supplement (DHA) to reduce triglyceride levels in patients currently being treated with statin therapy (Zocor or simvastatin, Lipitor or atorvastatin, Pravachol or pravastatin, Crestor or rosuvastatin, etc.) for coronary artery disease(CAD)or risk equivalents (any of the following: heart attack, post angioplasty or stent, post coronary bypass surgery, angina, vascular disease, stroke or diabetes). The rationale for the study is based around the finding that patients with CAD have an approximately 20 % reduction in the risk of sudden death when treated with fish oil (DHA is one of the ingredients in fish oil). In studies of statin-based therapies, it has been observed that statins reduce the risk of coronary events 20-45%. There has not yet been research trials exploring the combination of the two ingredients (i.e., DHA plus statin) in patient treatment either to reduce recurrent cardiac events or to address another reported finding of fish oils to lower triglyceride levels (triglyceride is a form of "blood fat"). This research project will be a pilot project to assess the safety and effectiveness of DHA "add-on" therapy in patients currently being treated with statins for CAD. The study hypothesis is to test the effectiveness of DHA as compared to placebo to lower triglyceride levels in the blood. This is a double-blinded randomized clinical trial.

NCT ID: NCT00349375 Completed - Hyperlipidemia Clinical Trials

Comparison of the Combination of Fenofibrate and 20 mg Simvastatin Versus 40 mg Simvastatin Monotherapy

Start date: November 2005
Phase: Phase 3
Study type: Interventional

Mixed or combined hyperlipidemia is a common metabolic disorder characterized by both hypercholesterolemia and hypertriglyceridemia. Statins and fibrates have complementary mechanisms and can be coadministered to patients with mixed hyperlipidemia. The overall objective of the study is to evaluate the efficacy and safety of combining fenofibrate and simvastatin in patients with mixed hyperlipidemia at risk of cardiovascular diseases.

NCT ID: NCT00345722 Completed - Clinical trials for Cardiovascular Diseases

The Effect of Strawberries in a Cholesterol-Lowering Dietary Portfolio

Start date: June 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether addition of strawberries to a dietary portfolio of cholesterol-lowering foods will improve compliance and so increase the effectiveness of the dietary portfolio in lowering cholesterol and improving cardiovascular risk factors.

NCT ID: NCT00345657 Completed - Dyslipidemia Clinical Trials

Efficacy Study of Extended-Release Niacin/Lovastatin Versus Usual Care

Start date: July 2003
Phase: Phase 4
Study type: Interventional

The purpose of this study is to investigate the benefits of combination niacin ER/lovastatin in patients receiving standard care who are not at LDL goal per ATP III guidelines.

NCT ID: NCT00331448 Active, not recruiting - HIV Infections Clinical Trials

Observational Study of Changes in Fat Distribution and Blood Metabolites in HIV Infected Adults

Start date: June 2000
Phase: N/A
Study type: Observational

The purpose of this study is to collect data on the body's breakdown of sugar and fat in HIV infected adults. Data from this study will make clearer the roles of HIV infection and anti-HIV drugs in the development of diabetes, heart disease, and fat redistribution in HIV infected adults.

NCT ID: NCT00316641 Recruiting - Hyperlipidemia Clinical Trials

The Clinical Evaluation of Efficacy of Lipid-Lowing Tea on Hyperlipidemia Patients’ Lipid Profiles

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether the Lipid-lowing Tea is effective and safe in the treatment of Hyperlipidemia Patients