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Hemorrhage clinical trials

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NCT ID: NCT00413946 Completed - Cerebral Palsy Clinical Trials

Does Erythropoietin Improve Outcome in Very Preterm Infants?

Start date: January 2006
Phase: Phase 2
Study type: Interventional

The main goal of this trial is to investigate whether early administration of human erythropoietin (EPO) in very preterm infants improves neurodevelopmental outcome at 24 months corrected age. This study is designed as randomized, double-masked, placebo controlled multicenter study involving at least 420 patients.

NCT ID: NCT00405626 Not yet recruiting - Hemorrhage Clinical Trials

Double Blind Placebo Controlled Bellis Perenis and Arnica Montana as a Drug for PPH

Start date: April 2007
Phase: Phase 1
Study type: Interventional

To look at the antihemmorhagic effect of 2 homeopathic drugs in women post delivery Bellis Perenis and Arnica montana

NCT ID: NCT00405613 Completed - Clinical trials for Bleeding Complication

Aspirin Use and Postoperative Bleeding From Dental Extractions in a Healthy Population

Start date: May 2003
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if aspirin is associated with bleeding complications following a single tooth extraction

NCT ID: NCT00401908 Withdrawn - Clinical trials for Acute Coronary Syndrome

Factors Contributing To Cardiovascular Morbidity and Mortality in Patients With Gastrointestinal Bleeding

Start date: November 2006
Phase: N/A
Study type: Observational

The rate of complication and death of patients with acute digestive tract bleeding is increased in the setting of acute coronary heart disease. The aim of the study is to establish the relative importance of the risk factors contributing to the death rate from acute digestive tract bleeding in patients admitted with acute coronary heart disease.

NCT ID: NCT00395993 Completed - Anemia Clinical Trials

Comparison of the Safety and Efficacy of Intravenous Iron Versus Oral Iron in the Treatment of Anemia Secondary to Heavy Uterine Bleeding

Start date: May 2005
Phase: Phase 3
Study type: Interventional

This study compares of the safety and efficacy of intravenous iron vs oral iron in the treatment of anemia secondary to heavy uterine bleeding

NCT ID: NCT00394849 Completed - Pain Clinical Trials

Effect of Tonsillar Pillar Closure on Postoperative Pain and Bleeding Risk After Tonsillectomy

Start date: July 2000
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if closing the tonsil fossa after tonsillectomy leads to less pain and bleeding risk than leaving it open to heal by secondary intention.

NCT ID: NCT00394771 Completed - Clinical trials for Breakthrough Bleeding

A Study to Evaluate Bleeding Patterns With Three Different Doses of DR-1031 Compared to Seasonale

Start date: October 2006
Phase: Phase 2
Study type: Interventional

This is a 4-arm study to evaluate and compare bleeding patterns between three different doses of DR-1031 oral contraceptive with Seasonale oral contraceptive. Study participants will receive physical and gynecological exams, including Pap smear. During the study, all participants will be required to complete a diary

NCT ID: NCT00378872 Completed - Hemorrhage Clinical Trials

Tranexamic Acid vs. Quixil - Reducing Blood Loss in Joint Replacement

Start date: June 2006
Phase: N/A
Study type: Interventional

We will compare the effectiveness of Quixil and Tranexamic acid in reducing bleeding during hip and knee joint replacements.

NCT ID: NCT00375466 Completed - Hemorrhage Clinical Trials

Tranexamic Acid, Hemorrhage and Transfusions After Combined Aortic Valve Replacement and Coronary Artery Bypass Surgery.

Start date: September 2006
Phase: N/A
Study type: Interventional

In this study we will investigate whether tranexamic acid given as an intravenous bolus injection before start of surgery, followed by a continuous infusion during surgery reduces, perioperative hemostatic activation, and postoperative bleeding and the need for transfusions of blood components in elderly patients undergoing combined aortic valve replacement and coronary artery bypass surgery. Tranexamic acid will be compared with placebo (0.9% sodium chloride) in a randomized and double-blind study design. The study hypothesis is that tranexamic acid will reduce hemostatic activation and postoperative hemorrhage and the need for blood component transfusions in this group of patients.

NCT ID: NCT00375258 Completed - Hemorrhage Clinical Trials

Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage

Start date: May 2005
Phase: Phase 3
Study type: Interventional

CRASH 2 is a large pragmatic randomised placebo controlled trial of the effects of the early administration of the antifibrinolytic agent tranexamic acid on death, vascular events and transfusion requirements. Adults with trauma who are within 8 hours of injury and have either significant haemorrhage, or who are considered to be at risk of significant haemorrhage, are eligible if the responsible doctor is for any reason substantially uncertain whether or not to use an antifibrinolytic agent. Numbered drug or placebo packs will be available in each participating emergency department. Randomisation will involve calling a 24-hour freecall randomisation service. The call should last only a minute or two and at the end of it the randomisation service will specify which numbered treatment pack to use. For hospitals where telephone randomisation is not feasible, randomisation will be by taking the next consecutively numbered treatment pack. No extra tests are required but a short form must be completed one month later or on discharge or on death (whichever occurs first).