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Hemorrhage clinical trials

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NCT ID: NCT01563380 Completed - Pain Clinical Trials

Role of Autologous Platelet Rich Plasma in Total Knee Arthroplasty

PRPTKA2012
Start date: January 2010
Phase: N/A
Study type: Interventional

This study was designed to evaluate the efficacy of leucocyte free autologous platelet rich plasma on blood loss, pain, wound healing and functional outcome after total knee arthroplasty. The investigators hypothesized that application of platelet rich plasma would help in reducing blood loss, postoperative pain and expedite wound healing and better short-term functional outcome following total knee arthroplasty.

NCT ID: NCT01562158 Completed - Clinical trials for Acquired Bleeding Disorder

Efficacy and Safety of Activated Recombinant Human Factor VII in Treatment of Bleeding in Patients Following Allogeneic Stem Cell Transplantation

Start date: April 2001
Phase: Phase 2
Study type: Interventional

This trial is conducted in Asia, Europe and Oceania. The aim of this trial is to evaluate the efficacy of placebo and activated recombinant human factor VII in patients having undergone allogeneic or autologous stem cell transplantation.

NCT ID: NCT01561417 Completed - Healthy Clinical Trials

Bioequivalence of NovoSeven® and a NovoSeven® Formulation Stable at Room Temperature in Healthy Male Subjects

Start date: April 2006
Phase: Phase 1
Study type: Interventional

This trial is conducted in Europe. The aim of this trial is to demonstrate bio-equivalence between the marketed activated recombinant human factor VII (NovoSeven®) (CP-rFVIIa) and a new formulation stable at 25°C (VII25).

NCT ID: NCT01541241 Completed - Clinical trials for Copper Intrauterine Device Induced Bleeding

Study About Patients Using Copper Intrauterine Device

IUD
Start date: January 2, 2012
Phase:
Study type: Observational

THE AIM OF THE this study is to assess the hemodynamic changes of uterine artery in patients with CIUD induced bleeding by using transvaginal color Doppler indices (uterine artery resistance index and pulsatility index) to prove the relationship between these changes and bleeding in these patient .

NCT ID: NCT01537263 Recruiting - Clinical trials for Aneurysmal Subarachnoid Hemorrhage

Ultrasound Perfusion Imaging After Aneurysmal Subarachnoid Hemorrhage

PSAB
Start date: January 2012
Phase: N/A
Study type: Observational

The purpose of this study is to examine wether delayed cerebral ischemia can be predicted by ultrasound brain perfusion imaging in patients with aneurysmal subarachnoid hemorrhage (SAH).

NCT ID: NCT01535781 Terminated - Anemia Clinical Trials

Study of the Effect of Tranexamic Acid Administered to Patients With Hip Fractures. Can Blood Loss be Reduced?

Start date: September 2011
Phase: N/A
Study type: Interventional

The effect of Tranexamic acid on blood loss, hemoglobin and transfusions in patients with pertrochanteric hip fractures. Tranexamic acid is a well known drug used in many types of surgery. The investigators wish to investigate if the use of tranexamic acid can reduce the peri- and post-operative blood loss in patients who undergo surgery with a short intramedullary nail, for a pertrochanteric hip fracture. An interim analysis was planned when reaching 60 inclusions. The interim analysis was conducted only on the primary outcome (TBL). A difference in TBL of no less than 500 ml was considered a reason to halt the study. The 0.001 level was chosen as a simple approach to this interim analysis from the Haybittle-Peto boundary

NCT ID: NCT01532661 Completed - Bleeding Clinical Trials

National Registry of rFVIIa (Novoseven) in Haemorrhagic Traumatology

NOVO7
Start date: April 2008
Phase: N/A
Study type: Observational

The rFVIIa (Novoseven) has been tested in traumatic hemorrhage but its efficiency has not been proven yet in this context. A national register has been set up in France identifying the patients which received rFVIIa. Those patients had persistent and active bleeding after severe trauma despite surgery and/or interventional radiology embolization. The aim of this present study is to report the first clinical results in those situations of patients treated with rFVIIa.

NCT ID: NCT01527357 Completed - Clinical trials for Mild or Moderate Surgical Bleeding

A Study of Fibrocaps™ in Surgical Bleeding

FINISH-3
Start date: May 21, 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to confirm the superiority of Fibrocaps plus gelatin sponge, as compared to gelatin sponge alone, for achieving hemostasis. The investigational products were used in participants with mild to moderate surgical bleeding during spine, liver, vascular or soft tissue surgery, when control of mild to moderate bleeding by standard surgical techniques is ineffective and/or impractical.

NCT ID: NCT01516671 Active, not recruiting - Clinical trials for Subarachnoid Hemorrhage

Neuroinflammation and Bispectral Index After Subarachnoid Hemorrhage

Start date: November 2011
Phase: N/A
Study type: Observational

Subarachnoid hemorrhage (SAH) is associated with a high mortality and frequently leads to severe disability in survivors caused by cerebral vasospasm and infarction. This study aims to elucidate the role of neuroinflammation (endocannabinoids and cortisol levels in cerebrospinal fluid) in the pathophysiology of cerebral vasospasm and the value of the bilateral bispectral index (BIS) for the early diagnosis of cerebral vasospasm.

NCT ID: NCT01516658 Completed - Clinical trials for Subarachnoid Hemorrhage

HYdrogel Coil Versus Bare Platinum Coil in Recanalization Imaging Data Study

HYBRID
Start date: June 2012
Phase: N/A
Study type: Interventional

HYBRID study is prospective randomized open label controlled multi center trial, to compare Hydrocoil and bare platinum coil for recanalization after endovascular treatment of intracranial aneurysms.