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Hemorrhage clinical trials

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NCT ID: NCT03463070 Not yet recruiting - Clinical trials for Post Partum Hemorrhage

Misoprostol Before and After Cesarean Section

Start date: March 2018
Phase: Phase 3
Study type: Interventional

comparison of the effect of misoprostol before and after cesarean on the blood loss

NCT ID: NCT03459378 Completed - Liver Cirrhosis Clinical Trials

Outcome After TIPS

Start date: March 23, 2018
Phase:
Study type: Observational

This clinical trial is a retrospective single-centre study. Research data will be acquired via patient histories stored in the hospital data system. Data of patients who received a Transjugular Intrahepatic Portosystemic Shunt (TIPS) at the University Hospital Graz between 1.1.2004 and 31.12.2017 will be included into the study. The aim is to investigate the outcome (transplantation free survival, time to (re)occurrence of ascites, occurrence of hepatic encephalopathy) of patients with portal hypertension after TIPS.

NCT ID: NCT03458000 Completed - Clinical trials for Upper Gastrointestinal Bleeding

Capsule Endoscopy for HEmorrhage in the ER

CHEER
Start date: April 17, 2018
Phase: N/A
Study type: Interventional

This is a multi-center randomized controlled trial examining the use of Video Capsule Endoscopy (VCE) to discharge low-moderate risk patients with suspected upper gastrointestinal bleeds (UGIB) from the Emergency Department (ED.) The investigators will enroll 100 subjects at 4 sites who present with signs of hemodynamically stable UGIBs and compare VCE risk assessment to an Active Control (AC) group who receive inpatient upper endoscopy (EGD).

NCT ID: NCT03452722 Completed - Brain Injuries Clinical Trials

Neuroinflammatory Response in Patients With ICH and IVH Treated With rtPA

Start date: June 1, 2011
Phase:
Study type: Observational

This study compares the neuroinflammatory response in patients with hypertensive ICH associated with IVH treated with intraventriculary applied rtPA, and the control group. The inflammatory mediator concentration is analyzed in local cerebrospinal liquor.

NCT ID: NCT03449420 Completed - Clinical trials for Post Partum Hemorrhage

Predictability of Thromboelastography Parameters in Severe Post Partum Hemorrhage

Start date: January 2012
Phase: N/A
Study type: Observational

The aim of the study is to determine if thromboelastography parameters can be predictive of severe post partum hemorrhage.

NCT ID: NCT03449342 Completed - Clinical trials for Congenital Bleeding Disorder

Research Study to Look at Side Effects During Regular Injection With Factor VIII Medicine Named Turoctocog Alfa for a 8 Weeks Period

guardian 10
Start date: March 1, 2018
Phase: Phase 4
Study type: Interventional

This study will test the well-known medicine turoctocog alfa for any side effects. The purpose is to test turoctocog alfa for any side effects in the Indian population. The participants will get turoctocog alfa. Turoctocog alfa is already a well-known medicine in India, and can be prescribed by the study doctor. The participants will get an injection every second day or 3 times per week. This is decided by the study doctor. The study doctor will decide the amount and how often the participants must take the medicine. The study will last for about 16 weeks. The participants will have 5 visits with the study doctor. If the participants agree to participate in this study, the participants will receive the first injection at the second visit, thereafter the participants will be trained to do the injection by themself.

NCT ID: NCT03444792 Completed - Clinical trials for Post Operative Hemorrhage

Mechanical Dilatation of the Cervix at Elective Caesarean Section to Reduce Post-Operative Blood Loss

Start date: February 10, 2018
Phase: N/A
Study type: Interventional

obstetric hemorrhage remains one of the major causes of maternal death in both developed and developing countries. Because of its importance as a leading cause of maternal mortality and morbidity, and because of evidence of substandard care in the majority of fatal cases, obstetric hemorrhage must be considered as a priority topic for national guideline development. Some obstetricians believe that the cervix of women at non-labor cesarean section is undilated and might cause obstruction of blood or lochia drainage, leading to postpartum hemorrhage and endometritis from the collection of lochia or debris. Dilatation of the cervix helps with the drainage of blood during postpartum, reducing intrauterine infection or the risk of postpartum hemorrhage. To avoid this problem, some obstetricians routinely dilate the cervix from above during an elective/ non-labor cesarean section using finger, sponge forceps or other instruments

NCT ID: NCT03444077 Not yet recruiting - Trauma Clinical Trials

Impact of a Prehospital Identification of Trauma Patients in Need for Damage Control Resuscitation.

Start date: July 2018
Phase: N/A
Study type: Interventional

Early identification of trauma patients in need for Damage Control Resuscitation (DCR) has potential to be beneficial for general emergency units that are not expected to be ready for this rare situation 24 hours per day, 7 days per week. It could also be useful for high performing trauma centers to identify such patients earlier and be able to provide earlier adequate treatment. By contrast, initiation of DCR in patients who do not require this aggressive therapy may negatively affect their survival. An early identification of patients who do not require DCR would probably be beneficial (impact on cost-effectiveness and on patients' survival). The evidence of the Trauma Induced Coagulopathy Clinical Score (TICCS) accuracy has been evaluated in several studies but the potential effect of its use on patient outcomes needs to be evaluated. There has never been any evaluation of the impact of a prehospital discrimination of trauma patients with or without the need for DCR. The primary objective of this study is to evaluate the impact on mortality of a prehospital discrimination between trauma patients with or without a potential need for DCR. Secondary objectives include evaluation of the feasibility of such discrimination and its impact on cost-effectiveness. We hypothesize that the information will lead to improved quality of care with reduced mortality and morbidity.

NCT ID: NCT03442608 Not yet recruiting - Hypothermia Clinical Trials

Trial of Long-term Therapeutic Hypothermia for Poor-grade Aneurysmal Subarachnoid Hemorrhage

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

This study is a prospective, multi-centre, randomized,controlled trial to compare the efficacy of long-term mild hypothermia with normothermic intensive management in patients with poor-grade aneurysmal subarachnoid hemorrhage. The primary hypothesis is that the induction of mild hypothermia (maintained at 32-35℃) for at least 5 days would improve the outcome of patients at six months post hemorrhage compared with normothermia.

NCT ID: NCT03442491 Not yet recruiting - Clinical trials for Postpartum Hemorrhage

Hayman's Haemostatic Suture to Treat Severe Post-partum Haemorrhage

HAYMAN-1
Start date: June 1, 2022
Phase:
Study type: Observational

Post-partum haemorrhage continues to be a leading cause of maternal mortality and morbidity, accounting for more than 125 000 deaths per year across the world. Prompt diagnosis and effective action are the cornerstones of management and are crucial to prevent fatal maternal haemorrhage. Considering that published data are extremely limited, the aim of our study will be to evaluate retrospectively the efficacy of Hayman's Haemostatic Suture for the treatment of resistant post-partum hemorrhage resistant to pharmacological therapy.