Heart Failure Clinical Trial
To investigate trends in the incidence and survival rates of congestive heart failure (CHF) in two successive cohorts of elderly people (1970-74, 1990-94) in a health maintenance organization (HMO).
BACKGROUND:
The study constituted part of a growing body of research designed to understand not only the
secular trends in mortality, morbidity, survival, and disability levels for selected major
chronic diseases among older persons in the United States, but also the implications of the
findings for health care utilization.
DESIGN NARRATIVE:
The design was that of a retrospective study of successive cohorts of a well-defined and
well-documented elderly population for the purpose of identifying and explaining trends in
congestive heart failure (CHF) incidence, survival, comorbidities and health services
utilization during the 25-year period 1970-1994. The study sample consisted of two
successive period cohorts of elderly people, identified for each of two five-year periods,
1970-1974 and 1990-94. The study tested the following hypotheses: 1) incidence of CHF had
decreased among the younger old (65-74 years of age); 2) incidence of CHF had increased
among the older old (75 years of age or above); 3) one-year survival time had increased
following onset of incident CHF; and 4) prevalence of hypertension had decreased and
prevalence of myocardial infarction and other manifestations of coronary artery disease
increased among incident cases of CHF.
The study completion date listed in this record was obtained from the "End Date" entered in
the Protocol Registration and Results System (PRS) record.
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