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Clinical Trial Summary

This study aims to evaluate cardiopulmonary interactions in patients with heat failure


Clinical Trial Description

Heart failure is one of the most common diseases, especially in ageing populations, affecting ≥10% of persons 70 years of age or older. There is a growing body of evidence that dyspnea in patients with heart failure is not only related to low cardiac output and pulmonary venous congestion, but also to functional and structural alterations of the lungs.Pulmonary hypertension is a well-known complication of heart failure, but recent evidence suggests that the alveolo-capillary membrane is also affected, at least in subgroups of patients with heart failure. Damage to the alveolo-capillary membrane is reflected by a low diffusion capacity of the lungs for carbon monoxide (DLCO). In this study we aim to describe the alteration of lung function and obtain morphometric data of the capillary bed of patients with heart failure. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03317314
Study type Observational
Source Hannover Medical School
Contact
Status Withdrawn
Phase
Start date July 1, 2017
Completion date December 31, 2017

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