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New-onset Heart Blocks After Noncardiac Surgery: a Retrospective Study of More Than 280,000 Patients

Heart Block Clinical Trial

Official title:
New-onset Heart Blocks After Noncardiac Surgery: a Retrospective Study of More Than 280,000 Patients

Clinical Trial Summary

This study aimed to investigate new-onset heart blocks after noncardiac surgery, identify risk factors, and develop a prediction model.

Clinical Trial Description

Objective: This study aimed to investigate new-onset heart blocks after noncardiac surgery, identify risk factors, and develop a prediction model. Methods: A retrospective cohort study included 281,497 patients aged 18 or older who underwent noncardiac surgery at a single center between Jan 2008 and Aug 2019. The main outcome was postoperative new-onset heart blocks within one year, including atrioventricular and bundle blocks. Prognostic impact was assessed using Kaplan-Meier survival curves and time-dependent Cox regression analysis. Perioperative data was used for machine learning models (logistic regression, support vector machine, random forest, decision tree). Model performance was measured using the area under the receiver operating characteristic curve (AUC). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06119009
Study type Observational
Source Chinese PLA General Hospital
Contact
Status Completed
Phase
Start date January 1, 2008
Completion date August 1, 2019
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