Healthy Clinical Trial
Official title:
IC-BASAROTs: Verification of a New Practice Method for More Accurate Bed-side Assessment of Individual Energy Expenditure
Assessment of resting energy expenditure (REE) by indirect calorimetry (IC) in 1400 healthy individuals for arithmetical transformation into an bedside tool to estimate energy requirements in dietary practice (BASAROTs). A multinational, multicenter, prospective cross-sectional study.
The assessment of energy expenditure is the basic requirement for any nutritional therapy.
Nevertheless, there is still no accurate, scientifically validated and practical bedside
tool.
The reference method for energy expenditure measurement is indirect calorimetry (IC). High
costs, time requirements and the need for trained personal are main reasons for its limited
use in clinical practice. Also arithmetical calculations, such as the Harris-Benedict
equation, are not widely accepted.
In general energy expenditure is often estimated by so called rules of thumbs, a method
requiring only one multiplication with body weight (for example: 25 kcal/kg body weight).
Sex, age and BMI are usually not considered, although they are independent predictors of
energy expenditure. Thus, energy expenditure estimations are often inaccurate, especially in
older and overweight/obese persons.
Therefore, it is important to develop a bedside tool that is more accurate but simple enough
to be accepted by practitioners. In 2004, the Austrian Society of Clinical Nutrition
published the first BMI, aged and sex adapted rule of thumbs, called BASAROTs (BMI Age Sex
Adjusted Rule Of Thumbs). Those were, however, based on results of the Harris Benedict
equation.
The main objective of the present study is, therefore, to replace the existing BASAROTs by
BASAROTs based on actual measurements of resting energy expenditure by indirect calorimetry
(IC-BASAROTs).
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