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Head and Neck Cancer clinical trials

View clinical trials related to Head and Neck Cancer.

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NCT ID: NCT04593589 Recruiting - Clinical trials for Head and Neck Cancer

Submandibular Gland Stem Cell Transplantation

RESTART
Start date: May 10, 2022
Phase: Phase 1
Study type: Interventional

This study is a phase I safety and feasibility study to treat head and neck cancer patients with autologous salivary gland stem cell transplantation after postoperative (chemo)radiotherapy.

NCT ID: NCT04585750 Recruiting - Breast Cancer Clinical Trials

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Start date: October 29, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

This Phase 1/2 study will assess the safety, tolerability, and efficacy of multiple dose levels of PC14586 (INN: rezatapopt) alone (monotherapy) and in combination with pembrolizumab in participants with advanced solid tumors containing a TP53 Y220C mutation.

NCT ID: NCT04574427 Completed - Clinical trials for Head and Neck Cancer

INtra-operative Evaluation of a Novel FLUorescENt C-mEt Tracer in Penile and Tongue

INFLUENCE
Start date: November 13, 2019
Phase:
Study type: Observational

In this study we evaluate the feasibility of intraoperative visualization of penile and tongue tumours using the fluorescent tracer EMI-137.

NCT ID: NCT04570839 Active, not recruiting - Ovarian Cancer Clinical Trials

COM701 in Combination With BMS-986207 and Nivolumab in Subjects With Advanced Solid Tumors.

Start date: August 31, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

This is a phase 1/2 open label sequential dose escalation and cohort expansion study evaluating the safety, tolerability and preliminary antitumor activity of COM701 in combination with BMS-986207 and nivolumab in patients with advanced solid tumors.

NCT ID: NCT04566393 Available - Colorectal Cancer Clinical Trials

Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies

Start date: n/a
Phase:
Study type: Expanded Access

The objective of this expanded access program is to provide ulixertinib (BVD-523) for compassionate use in advanced cancer patients with MAPK pathway-altered solid tumor(s), including but not limited to KRAS, NRAS, HRAS, BRAF, MEK, and ERK mutations who have incomplete response to or have exhausted available therapies. Ulixertinib is available for treatment as monotherapy or in combination with other clinically tolerable agent(s), conditionally approved by the drug manufacturer.

NCT ID: NCT04552587 Completed - Clinical trials for Head and Neck Cancer

The HEART Study (Healthy Eating and Recovery Together)

Start date: December 4, 2020
Phase: N/A
Study type: Interventional

Head and neck cancer survivors and their primary caregivers (N=25 dyads) will be enrolled to pilot test a nutrition support system with a care planning clinic visit and a caregiver mobile App. Participants will be asked to complete baseline and 6-week follow-up surveys. The clinic session (offered in person or remotely) will include a needs assessment and a tailored care plan with information, educational materials and referrals about participants' symptoms, behaviors, social concerns and caregiving tasks. After the visit, the program will provide an App for caregivers with follow-up resources and mobile support for one month.

NCT ID: NCT04545957 Recruiting - Prostate Cancer Clinical Trials

Jump: MR Simulation For Radiation Therapy Master Protocol

JUMP
Start date: October 14, 2020
Phase: N/A
Study type: Interventional

This is a master protocol for a prospective Phase I-II study evaluating feasibility and efficacy of incorporating magnetic resonance imaging (MRI) simulation into the planning of radiation treatments.

NCT ID: NCT04545632 Completed - Breast Cancer Clinical Trials

Docetaxel Ethanol-induced Symptoms; The Incidence and Risk Forecating Factor

DETECT
Start date: June 10, 2020
Phase:
Study type: Observational

To determine the incidence and risk factors of ethanol-induced symptoms, this multicenter, prospective, observational study is designed to include patients in Korea who are receiving chemotherapy with ethanol-containing docetaxel alone or in combination. Subjects who voluntarily provide written informed consent to provide information for this study and meet the inclusion/exclusion criteria will be given an enrollment number and will be followed during the observation period to collect study-related data in the Case Report Forms (CRFs) as predefined in the study protocol. Patients' decision to participate (or not) in this study will not affect their treatment (physician's prescriptions or diagnostic/therapeutic decisions).

NCT ID: NCT04544046 Active, not recruiting - Lymphoma Clinical Trials

Supportive Oncology Care At Home RCT

Start date: September 16, 2020
Phase: N/A
Study type: Interventional

This research study is evaluating a program that entails remote monitoring and home-based care for people with cancer who are receiving chemotherapy, radiotherapy, or chemoradiotherapy.

NCT ID: NCT04543045 Recruiting - Anxiety Clinical Trials

Qualitative Exploration of Head & Neck Cancer Patient Reported Experience of Radiotherapy

H&NPRER-RAC
Start date: May 5, 2021
Phase:
Study type: Observational

The study aims to explore the experience of patients with Head and Neck Cancer, who are preparing for and/or completed radiotherapy treatment.