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Gingivitis clinical trials

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NCT ID: NCT01630837 Completed - Gingivitis Clinical Trials

Frequency of Oral Hygiene

Start date: May 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the frequency of oral hygiene in the maintenance of gingival health in patients with an adequate method of oral hygiene.

NCT ID: NCT01601145 Completed - Gingivitis Clinical Trials

Effect of Probiotic on the Plaque pH. A Randomized Double Blind Interventional Study

Start date: January 2012
Phase: Phase 4
Study type: Interventional

The aim of the present research protocol was to evaluate the effect of probiotics daily used, on the plaque acidogenicity of children. The null hypothesis was that the plaque acidogenicity would remain unchanged and not associate with the use of probiotics. Moreover, the in situ study will be carried out to investigate the plaque formation as biofilm in demineralised enamel specimens following the regular consumption of a probiotic product compared to a control group. Metabolic of the biofilm formed on of the enamel specimens resulting from the consumption will be evaluated over a period of 8 weeks.

NCT ID: NCT01593540 Completed - Periodontitis Clinical Trials

Clinical Examination of Metal Free Interdental Brushes

Start date: September 2010
Phase: Phase 4
Study type: Interventional

The aim of the study was to evaluate the clinical efficacy (Eastman Interdental Bleeding Index, Quigley and Hein) of a novel metal-free interdentalbrush compared to a classig metal-core interdental brush.

NCT ID: NCT01578603 Completed - Gingivitis Clinical Trials

Effects of Two Sugar Substituted Chewing Gums on Caries and Gingivitis Variables

Start date: January 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the effect of three times a day mastication, during a follow-up period of 4 weeks, of two sugar-substituted chewing gums on various factors associated with dental caries and gingivitis.

NCT ID: NCT01559987 Completed - Gingivitis Clinical Trials

Dental Plaque Removal Study

PAU2
Start date: February 2012
Phase: N/A
Study type: Interventional

The purpose of this research study is to investigate water flow in dental devices and to understand the function of water flow behind oral hygiene improvements. Understanding this mechanism may help with the design of future products.

NCT ID: NCT01549587 Completed - Pregnancy Clinical Trials

Oral Hygiene and Maternity Outcomes Multicenter Study (OHMOM)

OHMOM
Start date: February 2012
Phase: N/A
Study type: Interventional

This study will track changes in oral health in pregnant women. Subjects will be assigned to either regular oral care or advanced oral care and be given oral care products to use until they deliver. A comparison between the two groups (regular and advanced oral care) will be made to see if the oral care products impacted oral health and maternity variables.

NCT ID: NCT01419626 Completed - Gingivitis Clinical Trials

A Study to Determine the Effects of Adding an Experimental Device With Mouthrinse to Oral Care Regimen

Start date: July 31, 2011
Phase: N/A
Study type: Interventional

The study will determine the effects of adding mechanical plaque control to a person's oral care regimen. Participants who qualify to participate in the study will will have an equal chance of being assigned to one of three groups. They will be asked to follow their assigned oral care regimen, fill out subject diaries as instructed, and return to the clinic two weeks and four weeks afterward to have their mouths examined.

NCT ID: NCT01411618 Completed - Periodontitis Clinical Trials

Efficacy of Essential Oil Mouthwash With and Without Alcohol: a 3-Day Plaque Accumulation Model

Start date: June 2010
Phase: N/A
Study type: Interventional

The daily removal of supragingival dental plaque is a major factor in the prevention of caries, gingivitis and periodontitis. Proper control of bacterial plaque is obtained through the mechanical removal of the biofilm by the proper use of the toothbrush and floss. However, some studies have shown that the mean time of brushing tooth surfaces is less than that required to obtain a proper cleaning 1 and only 2-10% of the patients use dental floss regularly and effectively 2. In addition, it has been demonstrated that even after education and motivation of the patient to the proper use of toothbrush and floss, its compliance is reduced with time 3. The result is the persistence of plaque in some areas, particularly on the interproximal surfaces of teeth. Many studies have demonstrated the effectiveness and usefulness of antiseptic mouthwashes containing active ingredients such as chlorhexidine (CHX) and essential oils (EO) to prevent and control the formation of plaque and gingivitis, when used in addition to mechanical procedures 4-7. Chlorhexidine is still the gold standard for its antimicrobial action and high substantiveness, but side effects, such as pigmentation, taste alteration and the formation of supragingival calculus limit its continued use 8. Essential oil (EO) mouthwashes have been used for years as an adjunct to brushing in addressing oral hygiene. Their effectiveness in controlling plaque and gingivitis are well documented in literature 9-14. They kill microorganisms by destroying their cell walls and inhibiting their enzymatic activity 15,16. Furthermore, phenolic compounds like EOs are known to interfere with the inflammation process 17,18. The antibacterial action is particularly effective for the ability of the mouthwash with EOs to penetrate the biofilm 19-21. The traditional EO mouthwashes contain ethanol, a chemical used to dissolve numerous substances in mouthwashes, including CHX. The concentration of ethanol present in the mouthwash with EOs is more than 20%, sufficient to dissolve the EOs but not enough to carry out a direct antibacterial effect 22,23. Many aspects against the use of alcohol in mouthwashes, such as its effects on the surfaces of composite restorations 24 and its possible role in the formation of oropharyngeal cancer are being discussed 25,26. Although a direct correlation of the cause and effect between the occurrence of oropharyngeal cancer and the use of mouthwashes with alcohol 27, has not demonstrated so far, it is considered desirable to eliminate ethanol for use in daily mouthwash, bringing in search of new formulations. Recently, an EOs containing mouthwash without alcohol was introduced on the European market (Daycare, Curaden, Kriens, and Suisse). To our knowledge, to date there are no published data on the effectiveness of this antimicrobial product. The rinsing with this mouthwash can cause fewer side effects but, in contrast, it may be less effective. The aim of this study was to evaluate the inhibitory properties of a new alcohol free EO containing mouthwash with respect to the traditional mouthwash containing 21.3% ethanol, through a standard 3-days plaque regrowth model.

NCT ID: NCT01388023 Completed - Gingivitis Clinical Trials

Day Long Prevention of Oral Malodor With a Palatal Patch (SmellX) Containing A Herbal Formula

SmellX
Start date: January 2008
Phase: Phase 2
Study type: Interventional

In a previous study the prevention of halitosis by the herbal formula and delivery system (SmellX), were established both in vitro and clinicaly. The duration of relief was established as long as 8 hours. In this study the investigators intend examine the day long efficacy of SmellX.

NCT ID: NCT01336179 Completed - Clinical trials for Plaque Induced Gingivitis

Comparative Effect of Chewing Sticks and Toothbrushing on Plaque Removal and Gingival Health

Start date: March 2011
Phase: N/A
Study type: Interventional

The purpose of the proposed study is to compare the effect of chewing sticks (Miswak) and the toothbrushes on plaque removal and gingival health.