General Anaesthesia Clinical Trial
Official title:
Comparison of the Non-invasive CNAP Pulse Pressure Variation With the Invasive Gold Standard
Noninvasive pulse pressure variation for the guidance of perioperative fluid therapy is
compared with the gold standard of invasive measurements. Cardiac output is derived by the
PICCO monitor.
Hypothesis: Noninvasive CNAP PPV predicts fluid responsiveness. A grey zone for the
prediction of fluid responsiveness will be defined.
Accuracy of PPV measured by two devices,PICCO and CNAP, is compared with the manually calculated PPV from the arterial line waveform. Established tests like passive leg raising and end-expiratory occlusion are used for prediction of fluid responsiveness. Intraoperative events like volume challenge are monitored. ;
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