Clinical Trials Logo
  1. Home
  2. General Anaesthesia
  3. NCT00506246

Efficacy and Safety Study of Two Propofol Formulations

General Anaesthesia Clinical Trial

Official title:
A Multi-Center, Randomized, Double-Blind, Positive Controlled Study to Evaluate the Efficacy and Safety of Propofol(Propofol®-Lipuro) in Total Intravenous Anaesthesia

Clinical Trial Summary

The purpose of the study to compare Propofol-MCT/LCT with LCT in terms of their efficacy and safety during total intravenous anaesthesia

Clinical Trial Description

Propofol (chemical substance 2, 6-Diisopropylphenol) is a short-acting intravenous general anaesthetic which is used for induction and maintenance of a general anaesthesia, for long-term sedation of ventilated intensive care patients or for short-term sedation in diagnostic and surgical procedures. As an active substance propofol produces good and readily controlled anaesthesia with smooth and problem-free recovery both in adult patients and in children over 1 month of age. One potential advantage of this formulation is that the MCT/LCT-emulsion reduces pain on injection, a frequently reported adverse reaction with LCT-emulsions of propofol. ;

Study Design

Allocation: Randomized, Endpoint Classification: Bio-equivalence Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00506246
Study type Interventional
Source B. Braun Melsungen AG
Contact
Status Completed
Phase Phase 3
Start date June 2007
Completion date October 2007
View Details
See also
  Status Clinical Trial Phase
Completed NCT04125121 - Neuroplasticity Induced by General Anaesthesia N/A
Completed NCT03682198 - Neuro-Ox 2018: Assessment of Cerebral Oxygenation Under Three Clinically Relevant Conditions N/A
Completed NCT04215302 - Prediction Accuracy for Langeal Mask Unique TM Size in Pediatric Patient
Completed NCT03130413 - Comparing Between Air-Q Intubating Laryngeal Airway and Ambu® AuraGain™ N/A
Active, not recruiting NCT00251810 - Can CSM Monitor Depth of Anaesthesia Just as Good as BIS? N/A
Terminated NCT02013869 - Low Flow Anaesthesia, is There a Difference Between 2 Modern Anaesthetic Machines Using Different Gas Reservoir N/A
Completed NCT05681611 - Effect of Rocuronium on BIS Values
Recruiting NCT01522508 - Evaluation of Analgesia Nociception Index (ANI) During Propofol/Remifentanil and Sevoflurane/Remifentanil Anesthesia N/A
Completed NCT04946110 - Electromagnetic Stimulation of the Phrenic Nerve of Intubated Patients N/A
Completed NCT02690389 - Electro-acupuncture and Flumazenil's Effect on Sedation N/A
Completed NCT02166580 - Accuracy of CNAP PPV Under General Anaesthesia N/A
Completed NCT01795482 - Preoperative Patient Warming for Prevention of Perioperative Hypothermia in Major Abdominal Surgery N/A
Completed NCT01549639 - Blood Propofol Measurement During Anaesthesia Using Propofol Target Controlled Infusion N/A
Completed NCT04771962 - Comparison of the Anaesthetic Gases in Maintainance of General Anaesthesia in Paediatrics Phase 1/Phase 2
Completed NCT03209323 - Epileptiform EEG Patterns During Induction of General Anaesthesia With Sevoflurane Compared to Those With Propofol N/A
Completed NCT05107167 - Electromagnetic Stimulation of the Phrenic Nerve of Intubated Patients With Obesity N/A
Completed NCT03669484 - Comparative Clinical Study of Efficacy and Safety of Remimazolam and Propofol in Patients Undergoing Elective Surgery Under General Anaesthesia Phase 3
Completed NCT03930966 - Association Between a Peri-traumatic Dissociation State and the Occurrence of Post-traumatic Stress Syndrome N/A
Completed NCT05789992 - Evaluation of Equivalent Minimum Alveolar Concentration (eMAC) During Propofol/Remifentanil Anesthesia N/A
Enrolling by invitation NCT04760912 - General Anesthesia With and Without Muscle Relaxation and Muscle Strength Recovery N/A