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Stress Ulcer Prophylaxis in the Intensive Care Unit — SUP-ICU  

Gastrointestinal Bleeding Clinical Trial

Official title:
Stress Ulcer Prophylaxis in the Intensive Care Unit (SUP-ICU)

Clinical Trial Summary

Stress ulcer prophylaxis (SUP) is standard of care in the intensive care unit (ICU), however the quantity and quality of evidence is low and potential harm has been reported. The aim of the SUP-ICU trial is to asses the overall benefits and harms of SUP with proton pump inhibitor in adult critically ill patients in the ICU.

Clinical Trial Description

Critically ill patients in the ICU are at risk of stress related gastrointestinal (GI) bleeding, and SUP is recommended. However, the quantity and quality of evidence supporting SUP is low and has been questioned. Furthermore studies have shown that proton pump inhibitors (PPIs) may increase the risk of pneumonia, clostridium difficile infection and acute myocardial ischemia. The aim of the SUP-ICU trial is to assess the benefits and harms of SUP with PPI in adult critically ill patients in the ICU. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02467621
Study type Interventional
Source Scandinavian Critical Care Trials Group
Contact
Status Completed
Phase Phase 4
Start date January 2016
Completion date January 21, 2018
View Details
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