Anticoagulation After GI Bleeding Pilot Study & Registry

Status Recruiting

Clinical Trial Summary

PANTHER-GI Pilot Study will assess the feasibility of a full-scale multicentre cohort management study evaluating the safety of a standardized strategy for resuming direct oral anticoagulants (DOACs) after major DOAC-related gastrointestinal (GI) bleeding among patients at moderate to high risk of re-bleeding and thrombosis. A parallel registry will assess whether eligible patients who are not enrolled in the PANTHER-GI Pilot Study are systematically different than enrolled patients and to explore barriers to enrolment.

Clinical Trial Description

This pilot cohort management study will evaluate a protocolized strategy for resuming DOACs after major GI bleeding based on thrombotic risk among patients at moderate to high risk of rebleeding. The timeframe for resuming DOACs will be determined based on the patient's underlying thrombotic risk. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05290857
Study type	Interventional
Source	Ottawa Hospital Research Institute
Contact	Deborah M Siegal, MD
Phone	613-737-8899
Email	dsiegal@toh.ca
Status	Recruiting
Phase	N/A
Start date	March 31, 2022
Completion date	December 2025

View Details

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Anticoagulation After GI Bleeding Pilot Study and Registry — PANTHER-GI

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms