Quality of Life Clinical Trial
Official title:
A Survey of Fatigue and QoL Among Gastric Cancer Patients Undergoing Major Abdominal Surgery
Background: Cancer-related fatigue (CRF), one of the indicators of QoL, is one of the most
common side effects of cancer and its treatment. However, the pathophysiological mechanisms
involved in CRF among cancer patients are not completely understood. Therefore, more in-depth
researches on CRF of surgical patients suffering from gastric cancer are needed in Taiwan.
Purpose: The purpose of this study is to examine the incidence rate and correlated factors
(QoL and immune biomarkers) of CRF among gastric cancer patients undergoing major abdominal
surgery.
Method: A longitudinal study was conducted to recruit gastric cancer patients who scheduled
to operate at surgical clinics from a northern medical center in Taiwan. The data will be
collected with a structured questionnaire and Immune markers assessments via purposive
sampling of 120 subjects. Before operation, on day 1 after operation, and on day 7 after
operation, the biomarkers will be measured. The BFI-T questionnaire will be filled out before
surgery and on day 1, 2, 7, 28 after surgery; The EORTC QLQ-C30 and EORTC QLQ-STO22
questionnaire will be filled out before surgery and on day 7, 28 after surgery; Type D
scale-14(Taiwanese version) questionnaire will be filled out before surgery and on day 28
after surgery. Data will be analyzed by using descriptive statistics, paired t-test, Chi
square test, Pearson's correlation, and the generalized estimating equation (GEE) was used to
identify significant factors with QoL after operation.
Anticipated achievement: The anticipated achievement of this study is to provide healthcare
providers with more knowledge about CRF, and help them to enhance the quality of life on
gastric cancer patients in the future.
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