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Fractures, Bone clinical trials

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NCT ID: NCT03092466 Recruiting - Hip Fractures Clinical Trials

Early Femoral Block in Elderly With Hip Fracture

Start date: February 26, 2017
Phase: N/A
Study type: Interventional

Assess if the addition of an early femoral nerve block (performed within 2 hours from the admission in emergency department through a femoral nerve catheter) in the elderly patients (> 70 years) with hip fracture, reduces the incidence of postoperative delirium assessed by CAM 3Ds test, compared to the traditional systemic pain therapy.

NCT ID: NCT03060876 Recruiting - Clinical trials for Proximal Humerus Fracture

Hanover Humerus Registry

HHR
Start date: June 2016
Phase: N/A
Study type: Observational [Patient Registry]

This register study collects data of patients with proximal humerus and humerus shaft fractures to monitor the healing process by assessing shoulder function and quality of life according to the treatment method (operative or conservative management).

NCT ID: NCT03056950 Recruiting - Rehabilitation Clinical Trials

BFR DISTRAD NON OP: Blood Flow Restricted Training During Rehabilitation Following Distal Radius Fracture

Start date: March 2016
Phase: N/A
Study type: Interventional

Occlusion training, resistance exercise performed with a specialized venous tourniquet, leads to beneficial changes in muscle strength at low resistance and minimal stress on the nearby joint. This novel resistance training has the potential to greatly improve muscle strength gains in individuals who are unable, for medical reasons, to perform the high resistance exercises typically required to improve strength. Our study will examine the effect of this technique on strength recovery following distal radius fracture treated with cast immobilization (non-operatively). The primary objective of the intervention is to achieve accelerated recovery of forearm, wrist and hand function as assessed using measures such as grip/pinch strength, validated questionnaires, and functional outcome testing. Occlusion training can potentially serve as a specialty intervention for rehabilitation patients, reduce the cost of care, and improve the treatment options for both patients and providers.

NCT ID: NCT03044015 Recruiting - Clinical trials for Osteoporotic Fractures

Primary Care Based Intervention for the Secondary Prevention of Osteoporotic Fractures

APROP
Start date: January 2017
Phase: N/A
Study type: Interventional

BACKGROUND Recent evidence has been published about the effectiveness for the secondary prevention of osteoporotic fractures (OF) of the hospital-based fracture liaison services. AIM To assess the effectiveness of a primary care based intervention in the secondary prevention of OF. METHODOLOGY Prospective study of random clusters, defined at the primary-care trust (PCT) level. Total study follow-up 3 years. Sample size 1800 patients. DESCRIPTION To launch a defined strategy for the identification of OF. To carry out a primary care based intervention about lifestyle, diet and drug prescription, if needed, with an intensive follow-up in the intervention PCT vs treatment as usual in the control branch. ANALYSIS As the outcome are the new OF, a survival analysis will be done. Risk factors will be analyzed through Cox proportional hazard regression model stratified by age groups. Outcomes : - new OF ratio in intervention vs control areas. - maintenance of the adherence to the pharmacological and non pharmacological interventions proposed - assessment of cost-effectivity of the intervention

NCT ID: NCT03026920 Recruiting - Clinical trials for Fracture Dislocation

Pelvic and Acetabular Fracture in Old People

Start date: June 2016
Phase: N/A
Study type: Interventional

It was reported that satisfactory postoperative outcome was difficult to obtain for the pelvic or acetabular fracture in old people. The less invasive surgical method was conducted in this study. Then, the clinical results were compared with the patients treated using traditional methods to assess the less invasive method.

NCT ID: NCT03026868 Recruiting - Clinical trials for Fracture Dislocation

Novel Quadrilateral Surface Plate for Acetabular Fracture

Start date: February 2015
Phase: N/A
Study type: Interventional

The novel plate could be used to manage acetabular fractures involving quadrilateral surface and posterior column, which may lower the intraoperative blood loss and reduce complication rate.

NCT ID: NCT03024008 Recruiting - Bone Fracture Clinical Trials

Enhancement of Bone Regeneration and Healing in the Extremities by the Use of Autologous BonoFill-II

Start date: July 27, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this clinical study is to evaluate the safety and the efficacy of BonoFill-II as an autologous bone-regenerating graft in the reconstruction of deficient bone in two clinical indications: 1. Long and short bone extra-articular comminuted fracture 2. Long and short bones extra and intra articular defect /Gap or non-union, incapable of self-regeneration

NCT ID: NCT02999022 Recruiting - Fractures Clinical Trials

Lithium for Fracture Treatment: a Double Blind Randomized Controlled Trial (LiFT)

LiFT
Start date: July 21, 2017
Phase: Phase 2
Study type: Interventional

This is a study designed to see if a low dose of Lithium treatment, taken for 2 weeks, can improve fracture healing and improve patients' function and productivity.

NCT ID: NCT02996383 Recruiting - Hip Fractures Clinical Trials

Fixation Versus Arthroplasty for Undisplaced Intracapsular Fractures

Start date: May 2016
Phase: N/A
Study type: Interventional

In England each year over 70,000 people fracture their hip. Most of these patients are elderly females with the fracture occurring after a simple trip or stumble. Approximately half of these fractures are classified from their relationship to the hip joint capsule as intracapsular. These fractures are subdivided into those that are displaced and those that are undisplaced. The majority of displaced fractures are treated with a replacement arthroplasty. Current treatment for the undisplaced fractures is generally by internal fixation of the fracture using screws and a plate, although some centres prefer replacement arthroplasty. A recent randomised study on patients from Norway with undisplaced intracapsular fractures treated with either internal fixation or arthroplasty has just reported reduced complications and re-operations for those patients treated with an arthroplasty. In addition functional results were marginally better for those patients treated with an arthroplasty. Current practice in the UK is generally to treat these fractures by internal fixation. This study aims to see if replacement arthroplasty can indeed lead to the advantages suggested from the Norwegian study. Patients who satisfy the inclusion criteria and are willing to participate will be randomised to receive either reduction and internal fixation of the fracture with a screw and plate device or alternatively replacement of their femoral head with an artificial hip replacement (hemiarthroplasty). After surgery patients will receive the same treatment as normal and be discharge home when able, with follow-up review in the hip fracture clinic. Subsequent follow-up for the research project is by phone calls from a research nurse who is blinded to the type of treatment that the patient has received. There will be no additional investigations or out-patient follow-up visits for these patients in comparison to normal treatment protocols. Results of the study will ultimately be published in a medical journal.

NCT ID: NCT02963233 Recruiting - Trauma Clinical Trials

Type II Pediatric Supracondylar Humerus Fracture Management and Outcomes: A Prospective Multi-centre Cohort Study

Start date: July 2015
Phase: N/A
Study type: Observational

The treatment of pediatric supracondylar humerus fractures is controversial, but despite the injury's high incidence there is a lack of high level evidence to guide operative versus non-operative decision making for displaced fractures with an intact posterior cortex (Gartland Type II). This study aims to prospectively compare clinical, functional, and radiographic outcomes between operatively and non-operatively treated patients using a prospective multi-centre cohort design.