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Fatigue clinical trials

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NCT ID: NCT02755493 Completed - Sleep Deprivation Clinical Trials

Quantifying and Developing Countermeasures for the Effect of Fatigue-Related Stressors on Automation Use and Trust During Robotic Supervisory Control

Start date: April 2016
Phase: N/A
Study type: Interventional

This project proposes to both develop and test adaptive automation countermeasures for the effects of stressors such as sleep deprivation (SD) on human performance related to robotic tasks, and investigate the relationship between human trust and appropriate use of these countermeasures.

NCT ID: NCT02740959 Completed - Clinical trials for Cancer-related Fatigue

Effects of PG2 on Fatigue-Related Symptom Clusters

Start date: March 2016
Phase: N/A
Study type: Interventional

This study is for an "add-on" study to the "main" study (Protocol No.: PH-CP012). The information of patients from main study will be collected by questionnaire survey and actigraphy measurement to evaluate the relationship between fatigue, depression and sleep disorder and the efficacy of PG2 after treatment.The association between symptom cluster and circadian rhythm will be also further explored.

NCT ID: NCT02739620 Completed - Breast Cancer Clinical Trials

Alternative Exercise Program to Improve Skeletal Muscle Function and Fatigue in Cancer Survivors

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

Exercise training has beneficial effects in cancer survivors to minimize some of the side effects of cancer and its treatment and improve long-term prognosis, but there are numerous hurdles for individuals diagnosed with, and being treated for, cancer to participate in exercise programs. The goal of this research study is to begin to evaluate whether exercise training via neuromuscular electrical stimulation (NMES) has beneficial effects on skeletal muscle size and function in cancer survivors.

NCT ID: NCT02735161 Completed - Fatigue Clinical Trials

Fatigue and Exercise Training in Patients With Sarcoidosis

Start date: April 2016
Phase: N/A
Study type: Interventional

The aims of the current study is to explore if different exercise training protocols affect fatigue post-exercise, and if sarcoidosis-related fatigue and maximal and sub-maximal cardiopulmonary exercise test (CPET) variables change after a 4-weeks exercise training period.

NCT ID: NCT02733276 Completed - Fatigue Clinical Trials

Electroacupuncture vs. Sham Electroacupuncture for Treatment of Fatigue in Patients With Inflammatory Bowel Disease

Start date: January 2016
Phase: N/A
Study type: Interventional

Fatigue is a common symptom in inflammatory bowel diseaseI and persists despite clinical remission. Fatigue in patients with chronic diseases can be objectified by the FACIT-F scale. Acupuncture has been shown useful in the treatment of fatigue in various chronic diseases. This study evaluates the effect of electroacupuncture in the treatment of fatigue in patients with quiescent inflammatory bowel disease. Patients with inflammatory bowel disease and severe fatigue (FACIT-F score <38) who agree to participate in the study will be randomized to three different treatments: electroacupuncture vs. sham electroacupuncture vs. control group.

NCT ID: NCT02721745 Completed - Cognitive Fatigue Clinical Trials

Cause and Consequence of Neural Fatigue

Fatstim
Start date: May 23, 2016
Phase: N/A
Study type: Interventional

While the scientific community understands quite well why muscles ache after prolonged exercise, the origins of mental fatigue remain totally mysterious. Existing theories remain at a psychological level, with scarce supporting evidence. Mental fatigue typically occurs after long episodes during which humans exert control on motor or cognitive processes, instead of executing routine or stimulus-driven behaviours. However, work organization (especially in risky job like airplane control or medical profession) and pathologies due to an overload of work (like burn-out) seems to be directly linked to neural fatigue. One of the consequences of neural fatigue is to alter decision-making. As an example, the choice between an immediate monetary reward and a larger but delayed monetary reward (the so called intertemporal choices) are susceptible to fatigue state of its underpinning neural network. The investigators are proposing an exploratory study of neural fatigue, induced either in a natural way (by performing cognitive tasks for hours) or by transcranial stimulation, using three main physiological measures (Electro-encephalography to measure neural activity, indirect calorimetry to measure the metabolic cost of a cognitive effort, and pupillometry to measure cognitive effort). This study should allow to better understand the consequences of neural fatigue on cognitive functions like decision making as well as the associated physiological variables.

NCT ID: NCT02719561 Completed - Fatigue Clinical Trials

Fatigue Intervention Co-design Study in Teenagers and Young Adults With Cancer

Start date: June 2016
Phase: N/A
Study type: Interventional

Fatigue is one of the most common and distressing symptoms in teenage and young adult cancer patients. Despite this, there has been virtually no research evaluating treatment for cancer-related fatigue in this young patient group. The investigators are undertaking a small qualitative study to co-design a fatigue intervention, that will then be evaluated in future research to assess its effectiveness.

NCT ID: NCT02712658 Completed - Clinical trials for Skeletal Muscle Fatigue in Humans

Role of K+ and Ca2+ in Development of Muscle Fatigue

Start date: September 2015
Phase: N/A
Study type: Interventional

The aim of the study is to investigate the role of K+ and Ca2+ in development of muscle fatigue in trained young men.

NCT ID: NCT02703935 Completed - Childhood Cancer Clinical Trials

Effectiveness of an Adventure-based Training Programme to Reduce Fatigue for Childhood Cancer Survivors

Start date: January 2014
Phase: N/A
Study type: Interventional

Background: Cancer-related fatigue is the most common concern reported by Childhood cancer survivors. Empirical evidence is needed to find out an appropriate strategy for ameliorating its impact. Purposes: To examine the effectiveness of an adventure-based training programme in promoting regular physical activity, reducing fatigue and enhancing quality of life among Hong Kong Chinese childhood cancer survivors. Design and Subjects: A randomised controlled trial (RCT), two-group pre-test and repeated post-test, between subjects design has been conducted. Recruitment of subjects has been carried out in an outpatient clinic, and through the Children's Cancer Foundation and Sunshine Group, which are non-profit voluntary organizations with the aim to provide education and supportive services to parents of Hong Kong Chinese childhood cancer survivors. Intervention: Participants in the experimental group have joined a four-day adventure-based training programme, which contains education talks, a workshop and adventure-based training activities. Those in the placebo control group has received an amount of time and attention (leisure activities organized by a community centre) that mimick that received by the experimental group.

NCT ID: NCT02690116 Completed - Fatigue Clinical Trials

Effects of Meditative Movement (Qigong/Tai Chi Easy) on Fatigued Breast Cancer Survivors

Start date: February 1, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to test whether Meditative Movement (based on a standardized and tested Qigong/Tai Chi Easy protocol) is more efficacious for improving fatigue and other symptoms in women after treatment for breast cancer than (a) a non-meditative "sham" Qigong active intervention and (b) an inactive education / support group.