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Fatigue clinical trials

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NCT ID: NCT06239142 Active, not recruiting - Clinical trials for Subarachnoid Hemorrhage, Aneurysmal

Understanding Mental Fatigue After Subarachnoid Hemorrhage

Start date: May 2015
Phase:
Study type: Observational

Fatigue is among the most frequently reported sequelae in stroke survivors. For a specific stroke diagnosis, aneurysmal subarachnoid hemorrhage (aSAH), fatigue, in general, is reported to be present in 30 to 90% of the patients. It is the mental fatigue component that significantly contributes to difficulties that patients with aSAH face when returning to normal life. However, there is substantial variation in the reported incidence of mental fatigue (25%-60%), which may be attributed to several methodological factors, such as differences in the follow-up periods and instruments used. Consequently, a complete understanding of how mental fatigue influences long-term recovery remains elusive. This research project will contribute to new and important knowledge in long-term effects after SAH when it comes to mental fatigue. In this study patients surviving an SAH will be assessed for mental fatigue at 5 years after the insult. The patients have previously been assessed at 1 and 3 years. All patients have been treated at Sahlgrenska University Hospital during the acute phase after SAH. Follow-up is performed after 5 years after aSAH through a structured telephone interview, where patients are scored using the Glasgow Outcome Scale-Extended (GOSE) Additionally, the patients receive a self-assessment questionnaire, the Mental Fatigue Scale, Patients are reminded to return the questionnaires at three times. This study aims to determine the long-term prevalence, severity, and dynamics of mental fatigue at 1, 3, and 5 years after an aSAH. The study also aims to identify whether demographic characteristics and secondary complications or diagnoses after aSAH can be associated with an increased risk of developing mental fatigue or unfavourable outcome.

NCT ID: NCT06233890 Active, not recruiting - Fatigue Clinical Trials

The Analysis of Fatigue on Tyrosine Kinase Inhibitor Therapy in Chronic Myeloid Leukaemia

TIRE
Start date: May 12, 2023
Phase:
Study type: Observational

The goal of this clinical study is to gain essential insights into the relationship between Tyrosine kinase inhibitor (TKI) therapy and profound fatigue and abnormal sleep patterns using rest-activity monitoring (actigraphy) and peripheral blood biomarkers in patients with Chronic myeloid leukaemia in chronic phase. The main aims are to 1. Determine the variance of subjective and objective sleep disturbance 2. Determine the difference in serum biomarkers (activin B and L-carnitine) 3. Determine how thes findings concord/discord between treatment and control groups. Participants will asked to undergo 2 weeks of actigraphy monitoring and keep a sleep diary during this time. Blood and urine samples will be taken for analysis. Researchers will compare two groups (patients with fatigue and those without) to assess the differences between groups.

NCT ID: NCT06201689 Active, not recruiting - Fatigue Clinical Trials

Radicle Energy 24: A Study of Health and Wellness Products on Fatigue and Related Health Outcomes

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

A randomized, double-blind, placebo-controlled study assessing the impact of health and wellness products on fatigue and related health outcomes

NCT ID: NCT06166043 Active, not recruiting - Multiple Sclerosis Clinical Trials

The Effect of the Nurses Support Program on Fatigue in MS Patient

Start date: January 30, 2023
Phase: N/A
Study type: Interventional

The research will be carried out as a randomized controlled experimental study to examine the effect of a nursing support program supported by a Web-based education program on the management of fatigue symptoms of patients who are under treatment and care in the Multiple Sclerosis clinic of a university hospital.Patients will receive 5 weeks of standard care. At the end of 5 weeks, they will enter a training program. After this online training program, which will be 5 weeks and 2 sessions per week, the change in the patients' fatigue, sleep quality and quality of life will be analyzed.

NCT ID: NCT06149897 Active, not recruiting - Stroke Clinical Trials

Feasibility and Effectiveness of tDCS in the Treatment of Post-stroke Fatigue (EFECTS).

EFECTS
Start date: November 10, 2023
Phase: N/A
Study type: Interventional

This study aims to analyze the use of non-invasive brain stimulation (tDCS) is beneficial for the treatment of post-stroke fatigue.

NCT ID: NCT06104891 Active, not recruiting - Fatigue Clinical Trials

Radicle Recharge: A Study of Health and Wellness Products on Energy Levels and Other Health Outcomes

Start date: October 25, 2023
Phase: N/A
Study type: Interventional

A randomized, double blind, placebo-controlled trial assessing the immediate impact of non-caffeinated supplements on energy levels and associated health outcomes

NCT ID: NCT06074627 Active, not recruiting - Fatigue Clinical Trials

Radicle Energy2: A Study of Health and Wellness Products on Fatigue and Other Health Outcomes

Start date: September 26, 2023
Phase: N/A
Study type: Interventional

A randomized, blinded, placebo-controlled study assessing the impact of health and wellness products on fatigue and other health outcomes

NCT ID: NCT05997082 Active, not recruiting - Clinical trials for Burnout, Professional

A Mindful Self-compassion Based Intervention for Specialist Rehabilitation Providers

Start date: July 13, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to explore the impact of an online compassion-based intervention on burnout among specialist rehabilitation providers. Post-intervention interviews aim to gather information on: burnout and compassion, experiences with the intervention, barriers and facilitators to taking part, and suggestions for improving online course delivery.

NCT ID: NCT05793736 Active, not recruiting - Pain Clinical Trials

Prevention of Long Covid Syndrome

Start date: February 2, 2023
Phase: N/A
Study type: Interventional

Biofeedback equipment is classified by the Food and Drug Administration (FDA) as medical device class II and this type of equipment/treatment has shown evidence regarding stress management in post-Covid-19 syndrome. The main objective of the study is to verify the feasibility of an HVR biofeedback training protocol in patients with long covid, and also to verify improvement induced by the technique in relation to: cognitive performance; pain perception; fatigue; quality of life; depressive and anxious symptoms

NCT ID: NCT05664711 Active, not recruiting - Clinical trials for Chronic Fatigue Syndrome

Effect of Stellate Ganglion Block on ME/CFS

SGB_ME
Start date: March 15, 2023
Phase: Phase 1
Study type: Interventional

The goal of this clinical trial is to study the effects of stellate ganglion block (SGB) in participants with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The main questions it aims to answer are: Does SGB treatment improve symptoms of ME/CFS (e.g. brain fog, fatigue)? Do changes in symptoms go along with changes in blood or saliva? Participants will receive a total of six blocks over three weeks (one block on each side, one day apart, per week). Prior to treatment and at two points following treatment, participants will complete surveys, take a cognitive (puzzle type) test, and provide blood and saliva for analysis. Participants will measure their heart rate daily using a free smart phone app.