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Exfoliation Syndrome clinical trials

View clinical trials related to Exfoliation Syndrome.

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NCT ID: NCT04202510 Withdrawn - Open Angle Glaucoma Clinical Trials

IOP and Medication Reduction in MIGS Procedures

Start date: January 6, 2020
Phase: N/A
Study type: Interventional

The primary objective of this research is to compare the efficacy of trabecular minimally invasive glaucoma surgery (MIGS) devices (iStent vs iStent Inject vs Hydrus) for intra ocular pressure (IOP) and anti-glaucoma medication reduction in open angle glaucoma.

NCT ID: NCT03798223 Active, not recruiting - Ocular Hypertension Clinical Trials

Optimal Treatment Protocol for Selective Laser Trabeculoplasty

OSLT
Start date: January 10, 2019
Phase: N/A
Study type: Interventional

A randomized controlled trial to evaluate which treatment protocol in selective laser trabeculoplasty that is most optimal in terms of efficacy and safety.

NCT ID: NCT03741153 Not yet recruiting - Lens Diseases Clinical Trials

Association Between Pseudoexfoliation Syndrome and Diabetes Mellitus

Start date: January 2019
Phase:
Study type: Observational

Pseudoexfoliation syndrome (PEX) is characterized by the deposition of a distinctive fibrillar material in the anterior segment of the eye and was first described in 1917 by Lindberg. It is frequently associated with open angle glaucoma, known as pseudoexfoliation glaucoma, which is one of the most common identifiable forms of secondary open angle glaucoma worldwide. Despite extensive research, the exactchemical nature of the fibrillar material is unknown. It is believed to be secreted multifocally in the iris pigment epithelium, the ciliary epithelium, and the peripheral anterior lens epithelium.

NCT ID: NCT03494465 Completed - Clinical trials for Intraocular Pressure

Efficacy and Safety of Lens Extraction in Patients With Pseudoexfoliation Glaucoma

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

There are several publications that have demonstrated the protective role of cataract surgery against the development of long-term glaucoma, especially in cases of pseudoexfoliation glaucoma (PXFG). Cataract surgery in patients with pseudoexfoliation (PXF) is a procedure with higher rates of complications due to its smaller pupillary diameter and its greater zonular weakness, so lens extraction performed earlier could possibly reduce intra and postoperative complications. Given the severity and high prevalence of PXFG in our environment, investigators proposed a randomized clinical trial to evaluate the efficacy of cataract surgery in reducing the intraocular pressure (IOP) at 12 months and thereby change the course of the disease. The control group will have glaucoma treatment according to standard practice.

NCT ID: NCT03483402 Completed - Clinical trials for Primary Open-angle Glaucoma

Micropulse Laser Trabeculoplasty as Adjunctive Treatment in Patients With Pseudoexfoliation Glaucoma

Start date: December 2016
Phase: N/A
Study type: Interventional

This study aims to evaluate the effect of a single session of micropulse laser trabeculoplasty (MLT) on cornea in eyes with primary open glaucoma (POAG) and pseudoexfoliation glaucoma (PEXG).

NCT ID: NCT03453827 Completed - Cataract Clinical Trials

Long-term Intraocular Lens (IOL) Decentration and Tilt in Eyes With Pseudoexfoliation Syndrome (PES) Following Cataract Surgery

Start date: April 1, 2016
Phase: N/A
Study type: Observational

To evaluate long-term intraocular lens (IOL) decentration and tilt in eyes with pseudoexfoliation syndrome (PES) following cataract surgery using Visante anterior segment OCT and iTrace Visual Function Analyzer.

NCT ID: NCT03445806 Terminated - Clinical trials for Glaucoma, Open-Angle

IOP Monitoring After Trabeculectomy Using iCare Home

Start date: February 26, 2018
Phase:
Study type: Observational

The purpose of this study is to investigate how much trabeculectomy influences intraocular pressure (IOP) fluctuations measured with iCare Home rebound tonometry (RTHome) in patients with primary open-angle glaucoma (POAG) or pseudo-exfoliation glaucoma (PEX).

NCT ID: NCT03423758 Recruiting - Glaucoma Clinical Trials

Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma

Start date: May 30, 2017
Phase:
Study type: Observational

There is increasing evidence that there are genetic risk factors for several forms of glaucoma, such as glaucoma caused by pseudoexfoliation syndrome (PXF) ,primary angle closure glaucoma (PACG) and primary open-angle glaucoma (POAG). The aim of the present prospective, multi-center, case-control study is to identify susceptibility genes/loci for PXF, PACG and POAG using a whole genome association (WGA) approach.

NCT ID: NCT03310788 Recruiting - Clinical trials for Glaucoma Open-Angle Primary

Monitoring of the IOP After SLT Using iCare Home

Start date: October 3, 2017
Phase:
Study type: Observational

The purpose of this study is to investigate how much selective trabeculoplasty (SLT) influences intraocular pressure (IOP) fluctuations measured with iCare Home rebound tonometry (RTHome) in patients with primary open-angle glaucoma (POAG) or pseudo-exfoliation glaucoma (PEX).

NCT ID: NCT03265457 Not yet recruiting - Clinical trials for Pseudoexfoliation Syndrome

The Endothelial Count in Pxf

Start date: October 1, 2018
Phase:
Study type: Observational

Pseudoexfoliation Syndrome Is a common disorder in Egypt. IT is one of the common causes of coexisting cataract and glaucoma. It may be associated with a less than normal endothelial count.