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Exfoliation Syndrome clinical trials

View clinical trials related to Exfoliation Syndrome.

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NCT ID: NCT06237764 Completed - Risk Reduction Clinical Trials

Genetic and Risk Factors in Exfoliation Glaucoma Patients

Start date: January 1, 2014
Phase:
Study type: Observational

Prospective non-randomised cohort study enrolling patients with exfoliation glaucoma. All patients were ophthalmological examined at inclusion. Blood samples were taken for genetic analysis.

NCT ID: NCT06154330 Recruiting - Clinical trials for Glaucoma, Open-Angle

Safety and Efficacy of Suprachoroidal Tube Shunt in Patients With Primary Open and Pseudoexfoliation Glaucomas

Start date: November 20, 2023
Phase:
Study type: Observational

To assess safety and efficacy of a novel suprachoroidal silicone tube (SST) shunt for the treatment of primary open angle and exfoliative glaucomas.

NCT ID: NCT06121154 Completed - Sarcopenia Clinical Trials

Pseudoexfoliation Syndrome, Sarcopenia and Chronic Pain

Start date: March 30, 2023
Phase:
Study type: Observational

Aim: Pseudoexfoliation syndrome (PEX) is a systemic disease of connective tissue, it can also contribute to sarcopenia and chronic musculoskeletal pain with common pathways. 1. First aim of this study was to investigate whether the rate of sarcopenia is higher in patients with PEX 2. Second aim was to investigate the association between PEX, sarcopenia parameters and chronic musculoskeletal pain. Methods: A total of 96-patients were enrolled in this study and divided into two groups: PEX-positive (n=48) and PEX-negative (n=48) patients. The variables: the demographic data, sarcopenia parameters (SARC-F-questionnaire, hand-grip strength, chair-rise test, gait speed) and pain parameters (having any chronic musculoskeletal pain, pain regions and visual analogue scale-pain).

NCT ID: NCT06053554 Recruiting - Clinical trials for Pseudoexfoliation Syndrome

Outcome of Two Surgical Methods for IOLImplantation in Eyes With Pseudoexfoliation Syndrome

Start date: September 18, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to compare the surgical outcomes of the two IOL implantation methods for eyes with cataract and PEX in a single-center and with highly experienced surgeons. The goal is to acquire relevant information regarding these two IOL implantation techniques, which will help surgeons to decide which approach to choose, ultimately resulting in a benefit for patients with PEX syndrome who require cataract surgery. The main questions are: Is there a difference in lens tilt and decentration between the both methods. Is there a difference in the frequency and amount of capsular phimosis between the both methods.

NCT ID: NCT05557721 Enrolling by invitation - Clinical trials for Primary Open Angle Glaucoma

Uddevalla Skövde Transscleral Micropulse Study

USTMS
Start date: October 6, 2023
Phase:
Study type: Observational

Micro pulse transscleral laser treatment (MP-TLT) is a relatively new method to reduce the intraocular pressure (IOP) in glaucoma. New recommendations regarding the treatment protocol has recently been developed and was published 2022. The overall objective is to evaluate the efficacy and safety of the proposed treatment method in an independent study. In addition, the outcome of MP-TLT in patients with pseudoexfoliation glaucoma, which is relatively common in the Nordic countries, and primary open angle glaucoma will be studied separately. The IOP change over the course of one year will be monitored, as well as success rate and survival. Further, patient-reported discomfort from the treatment and the occurrence of any adverse events or complications will be studied.

NCT ID: NCT05447130 Completed - Clinical trials for Pseudoexfoliation Syndrome

Corneal Endothelium After Phacoemulsification in Pseudo Exfoliation Syndrome

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

To study corneal endothelial cells changes after phacoemulsification in patients with senile cataract and pseudoexfoliation syndrome (PEX) compared with control patients with senile cataract using specular microscope.

NCT ID: NCT05439161 Not yet recruiting - Clinical trials for Primary Open Angle Glaucoma

XEN Glaucoma Gel Stent Versus Trabeculectomy

Start date: November 30, 2023
Phase: N/A
Study type: Interventional

Multicentric evaluation of best corrected visual acuity of the XEN implant versus classic trabeculectomy in open angle glaucoma subjects

NCT ID: NCT05159960 Enrolling by invitation - Ocular Hypertension Clinical Trials

Optimal Treatment Protocol for Selective Laser Trabeculoplasty - Repeat Trial

OSLT-R
Start date: January 10, 2022
Phase: N/A
Study type: Interventional

Glaucoma is a common eye disease that can lead to blindness. The only known way to reduce the rate of disease progression is by reducing the pressure in the eye (the intraocular pressure, IOP). Selective laser trabeculoplasty (SLT) is an ophthalmic laser intervention with the purpose of reducing the IOP. SLT can be performed in different ways, with four of the treatment protocols being evaluated in the Optimal SLT (OSLT) trial. SLT is a repeatable procedure, but scientific evidence is scarce regarding more than one repetition. In this trial, patients included in the OSLT trial will be invited to the extended trial (OSLT-R), for further follow-up and re-treatment with SLT, if needed.

NCT ID: NCT05156138 Recruiting - Clinical trials for Pseudoexfoliation Syndrome

The Possible Association Between Pseudoexfoliation Syndrome And Corneal Endothelial Cell Changes

Start date: January 24, 2022
Phase:
Study type: Observational

The study aims to compare the endothelial cell count in patients with pseudoexfoliation syndrome to the the endothelial cell count in normal patients above the age of 50.

NCT ID: NCT05113121 Completed - Clinical trials for Pseudoexfoliation Syndrome

Correlation Between Pupil Size and Ocular Signs of Pseudoexfoliation Syndrome

Start date: August 25, 2021
Phase:
Study type: Observational [Patient Registry]

To study possible correlation between the size of the pupil in both room light and after dilation between both eyes in bilateral pseudoexfoliation with Intraocular pressure, lens clarity and stability, Optic disc , Visual changes and glaucoma changes by optical coherence tomography