Clinical Trial Details
— Status: Completed
Administrative data
NCT number |
NCT04954729 |
Other study ID # |
2019-266 |
Secondary ID |
|
Status |
Completed |
Phase |
|
First received |
|
Last updated |
|
Start date |
June 1, 2019 |
Est. completion date |
June 30, 2021 |
Study information
Verified date |
July 2021 |
Source |
Second Affiliated Hospital, School of Medicine, Zhejiang University |
Contact |
n/a |
Is FDA regulated |
No |
Health authority |
|
Study type |
Observational
|
Clinical Trial Summary
Epilepsy with centrotemporal spikes (ECTS) is the most common epilepsy syndrome in children.
Language impairment has been widely investigated in patients with ECTS, but little is known
about the cognitive dysfunction of processing speed and its neuroimaging mechanism.
Description:
OBJECTIVE To investigate the processing speed dysfunction in patients with ECTS, and the
associated brain functional abnormality using functional magnetic resonance imaging (fMRI)
and 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET).
DESIGN, SETTING, AND PARTICIPANTS This study prospectively enrolled ECTS patients (n = 28)
from June 2019 and June 2021. Twenty age- and gender- matched healthy children and another
twenty children with extracranial tumors were enrolled as controls. Patients with ECTS and
healthy controls underwent neuropsychological testing and fMRI examination. In addition, ECTS
patients and children with extracranial tumors underwent 18F-FDG PET examination.