Epilepsy, Rolandic Clinical Trial
Official title:
Facial Emotion Decoding in Benign Partial Epilepsy of Childhood With Centrotemporal Spikes
The social processes depend on complex cognitive mechanisms, which involve mainly the frontal and temporal lobe regions. Patients with early onset frontal and temporal lobe lesions might later develop important deficits in social integration. Accordingly, children with early onset temporal lobe epilepsy (TLE) demonstrate altered emotion recognition.
Study design: Multicentre, Case-control study.
Emotion recognition is a first step for the development of the capacity to judge the
thoughts, intentions, and desires of others. In infants, the capacity to identify,
distinguish, and interpret emotions is limited, but these processes are developing rapidly
and innately during the first years of life, on the same neural bases as those described in
adulthood. Children with BECTS show altered social behavior. In fact, deficit in social
cognition could derive from brain dysfunction in the frontotemporal regions primarily
affected in BECTS, since these regions are also viewed as playing an important role in social
cognition and development of social skills.
The investigators hypothesized that children with BECTS might have altered social cognitive
skills and underlying neural networks.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT00471744 -
HEAD-Study Optimizing the Treatment of Children With BECTS
|
Phase 3 | |
| Completed |
NCT04954729 -
Association of Processing Speed Dysfunction and Brain Functional Abnormality in ECTS
|
||
| Completed |
NCT00216567 -
Safety and Efficacy of Topamax Versus Carbamazepine in Benign Rolandic Epilepsy
|
Phase 4 |