Clinical Trials Logo
  1. Home
  2. Emergencies
  3. NCT05919225

Risk Stratification Using MEESSI-AHF Scale in ED and Impact on AHF Outcomes — MEESSI  

Emergencies Clinical Trial

Official title:
Evaluation of the Impact of the MEESSI-AHF Scale on Decision Making and the Prognosis of Patients Diagnosed With Acute Heart Failure in the Emergency

Clinical Trial Summary

Evaluate the impact the application of the MESSI-AHF scale (a risk stratification scale specifically derived and validated in patients diagnosed with acute heart failure, AHF) in decision making (admission vs. discharge) by emergency physicians in emergency departments (ED) and its potential impact on on the short-term prognosis of patients with AHF.

Clinical Trial Description

Study 1: A non-intervention study involving the consecutive inclusion of 3,200 patients with AHF in 16 Spanish EDs managed according to the usual practice. Individual risk will be retrospectively stratified according to the MEESSI-AHF scale, and we will analyze the distribution of the categories of risk in patients admitted and discharged and the prognosis of patients with low risk discharged from the ED and compare the events observed in this subgroup of patients with the recommended international standards. Study 2: This is a cuasiexperimental study in 8 EDs with consecutive inclusion of 1,600 patients with AHF managed according to the usual practice (without stratification of risk, pre-phase) and 1,600 patients managed after the implementation of the MEESSI-AHF scales for risk stratification before the final decision making in the ED (post-phase). If the patient has low risk the calculator will propose discharge; for the remaining categories of risk the calculator will propose patient admission. The final decision corresponds to the attending physician and if this decision differs from what was proposed, a reason will be given. Study 3: Open multicentre (8 EDs) randomized clinical trial (1:1) comparing the results obtained in the patients randomized to usual clinical practice (1,600 patients) with those obtained in the patients randomized to the use of the MEESSI-AHF scale for risk stratification (1,600 patients) prior to decision making. The dynamics of the decision proposed by the scale will be the same as that in Study 2. Main outcomes (Studies 1, 2, 3): Death (by any cause and cardiovascular cause) at 30 days and at 1 year; combined event (revisit to the ED or hospitalization for AHF or death) at 30 days post-discharge (global analysis of all the patients with AHF stratified by categories of risk); days alive and outside the hospital at 30 days after the index event (consultation to the ED); and proportion of patients managed without hospitalization. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05919225
Study type Interventional
Source Hospital Clinic of Barcelona
Contact Oscar Miro, PhD
Phone (+34)638274489
Email omiro@clinic.cat
Status Recruiting
Phase N/A
Start date June 27, 2023
Completion date December 31, 2024
View Details
See also
  Status Clinical Trial Phase
Completed NCT05552989 - Towards Better Preparedness for Future Catastrophes - Local Lessons-learned From COVID-19
Not yet recruiting NCT04915690 - Investigation on the Practice Status of Emergency Stuff
Not yet recruiting NCT03424096 - Primary Palliative Care Education, Training, and Technical Support for Emergency Medicine N/A
Completed NCT02534324 - The Effect of Pre-discharge Blood Pressure of Patients With Asymptomatic Severe Hypertension in Emergency Department N/A
Completed NCT00991471 - The Effect of an Physician-Nurse Supplementary Triage Assistance Team on Emergency Department Patient Wait Times N/A
Recruiting NCT03257319 - Inhaled vs IV Opioid Dosing for the Initial Treatment of Severe Acute Pain in the Emergency Department Phase 3
Recruiting NCT05005117 - Laparoscopic Approach for Emergency Colon Resection N/A
Recruiting NCT03917368 - Ultrasound Evaluation of the Jugular Venous Pulse (US-JVP) N/A
Completed NCT04601922 - Qualitative Study of Long Term Cardiovascular Risk Prediction in the Emergency Department
Recruiting NCT05497830 - Machine Learning for Risk Stratification in the Emergency Department (MARS-ED) N/A
Active, not recruiting NCT06220916 - The Greek Acute Dance Injuries Registry
Recruiting NCT06072534 - Evaluation of Effectiveness of Two Different Doses of Mivacurium in Rapid Sequence Intubation N/A
Recruiting NCT05496114 - Medical Checklists in the Emergency Department N/A
Recruiting NCT05543772 - Evaluation of Blood Sampling From a Pre-existed Peripheral Intravenous Catheter Line Phase 4
Not yet recruiting NCT05528211 - Safety and Efficacy of Emergent TAVI in Patients With Severe AS
Completed NCT05818215 - Impact of the Qatar 2022 FIFA World Cup on PED Use and Misuse Patterns
Recruiting NCT04615065 - Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Active, not recruiting NCT05221697 - Effect of an ML Electronic Alert Management System to Reduce the Use of ED Visits and Hospitalizations N/A
Active, not recruiting NCT04648449 - Artificial Intelligence (AI) Support in Medical Emergency Calls
Not yet recruiting NCT04431986 - ER2 Frailty Levels and Incident Adverse Health Events in Older Community Dwellers