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Dyslipidemias clinical trials

View clinical trials related to Dyslipidemias.

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NCT ID: NCT05787002 Completed - Dyslipidemia Clinical Trials

A Study to Assess the Effect of AZD0780 on the Pharmacokinetics of Rosuvastatin.

Start date: March 9, 2023
Phase: Phase 1
Study type: Interventional

The purpose of the study is to assess the effect of AZD0780 on the pharmacokinetics of rosuvastatin, and to assess the safety and tolerability of AZD0780 single dose, in healthy participants administered alone and in combination with rosuvastatin.

NCT ID: NCT05764317 Completed - Clinical trials for Arterial Hypertension

Description of the Effectiveness, Safety, Tolerability and Adherence to Amlodipine/Atorvastatin/Perindopril Single Pill Combination Treatment in Patients With Arterial Hypertension and Dyslipidemia (TARGET)

TARGET
Start date: April 30, 2023
Phase:
Study type: Observational

This is a multi-centre, observational, ambispective study, which will retrospectively and prospectively collect clinical and socio-demographic data from medical records of patients with HTN and dyslipidemia initiated with SPC of amlodipine/atorvastatin/perindopril in real clinical settings. A total of 80 general practitioners and outpatient cardiologists will participate in this non-interventional study 400 patients should be included in the study.

NCT ID: NCT05749861 Completed - Clinical trials for Hypertension and Dyslipidemia

A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-348(5)

Start date: April 22, 2023
Phase: Phase 1
Study type: Interventional

A phase I clinical trial to evaluate the tolerability and the pharmacokinetics of CKD-348(5).

NCT ID: NCT05733455 Completed - Insulin Resistance Clinical Trials

Effect of Alpelisib in Healthy Volunteers

Start date: May 9, 2023
Phase: Phase 1
Study type: Interventional

The goal of this clinical trial is to test a single dose of the phosphoinositide-3-kinase (PI3K) inhibitor alpelisib versus placebo in healthy volunteers. The main questions it aims to answer are the impact of acute alpelisib-induced insulin resistance on parameters of glucose and lipid metabolism (how healthy people respond to temporary insulin resistance so that the investigators can see what happens to how the liver handles fat and sugar). Participants will: - Consume their total calculated daily caloric needs in nutritional supplements, divided in three meals, and otherwise fast for 24 hours - Take a dose of alpelisib 300 mg or placebo at bedtime - Wear a continuous glucose monitor for 72 hours - Participate in an oral glucose tolerance test (OGTT) Researchers will compare blood tests before and during OGTT in participants randomized (like the flip of a coin) to alpelisib versus placebo to see how the drug treatment affects plasma glucose, serum insulin, and serum lipid parameters (triglycerides, free fatty acids, and apolipoprotein B).

NCT ID: NCT05698043 Completed - Clinical trials for Hypertension and Dyslipidemia

A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-386(5) 80/20/10mg

Start date: July 17, 2023
Phase: Phase 1
Study type: Interventional

A Clinical Trial to evaluate the Pharmacokinetics and Tolerability of CKD-386(5)

NCT ID: NCT05634447 Completed - Dyslipidemias Clinical Trials

A Clinical Trial to Compare and Evaluate the Safety and Pharmacokinetics of CKD-391

Start date: December 20, 2022
Phase: Phase 1
Study type: Interventional

A clinical trial to compare and evaluate the safety and pharmacokinetics of CKD-391

NCT ID: NCT05572749 Completed - Obesity Clinical Trials

Clinical Trial of Crocus Kozanis Administration in Obese Children and Adolescents

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

The study aims to investigate possible effects of per os Crocus Kozanis administration in children and adolescents with obesity

NCT ID: NCT05555238 Completed - Dyslipidemia Clinical Trials

An Observational Study to Evaluate the Treatment of Newvast® Tab(Atorvastatin) in Korean Patients With Dyslipidemia

Start date: January 16, 2020
Phase:
Study type: Observational

In this study, dyslipidemia patients visited the institutions during the study period and the effectiveness and safety of the treatment of Newvast® Tab(Atorvastatin) in real-practice. During the routine medical visit, according to the investigator's judgment, with diagnosis that the Newvast® Tab(Atorvastatin) prescription is appropriate, regardless of medical history and concomitant-medication, and after deciding to start treatment, patients with Dyslipidemia who agreed to participate in the study were administered Newvast® Tab(Atorvastatin). As this study is a non-interventional observational study, all subjects received prescriptions according to the routine treatment procedure, and there were no visits or procedures required according to the observational study protocol.

NCT ID: NCT05552495 Completed - Clinical trials for Hypertension and Dyslipidemia

Clinical Study to Evaluate the Pharmacokinetic Profiles and Safety of CKD-386 in Healthy Volunteers Under Fasting Conditions

Start date: September 23, 2022
Phase: Phase 1
Study type: Interventional

This study is a randomized, open-label, single dose, crossover study to evaluate the pharmacokinetic profiles and safety of CKD-386 in healthy volunteers under fasting conditions.

NCT ID: NCT05549401 Completed - Clinical trials for Hypertension and Dyslipidemia

Clinical Trial to Evaluate the Tolerability and the Pharmacokinetics of CKD-348

Start date: September 29, 2022
Phase: Phase 1
Study type: Interventional

A phase I clinical trial to evaluate the tolerability and the pharmacokinetics of CKD-348.