Disorder, Major Depressive Clinical Trial
Official title:
An Innovative Smartphone-enabled Health Coaching Intervention for Youth Diagnosed With Major Depressive Disorders
Randomized controlled trial (RCT) comparing youth diagnosed with major depressive disorder treated with online mindfulness-based cognitive behavioural therapy vs. standard psychiatric care (as wait-list controls). Eligible subjects will be recruited from the wait-lists of the Centre for Addiction and Mental Health. N = 168 subjects will consist of youth from First Nations background (18-30 yrs) and youth from all other ethnic backgrounds stratified to two intervention groups and two wait-list control groups consisting of 50% First Nations youth and 50% youth of all other ethnic backgrounds.
A high proportion (70%) of mental health problems appear before 25 yrs. and can become become
long-standing, significant disorders that impair all life domains. Early signs of disorder
left untreated is an acute problem for Canadian youth as 15-25 yrs is the most likely
age-strata for diagnosable psychiatric disorders, substance dependencies and suicide.
Progress in youth treatments that engage the tendencies of youth to respond to online
internet contact are likely to be especially strategic.
In this randomized controlled trial (RCT) diagnosed depressed youth are treated with online
mindfulness-based cognitive behavioural therapy (MB-CBT) and standard psychiatric care or
just standard psychiatric care (as wait-list controls). Eligible subjects will be recruited
from the wait-lists of the Centre for Addiction and Mental Health (CAMH), and from
community-based practices and clinics proximal to CAMH. The consented 168 subjects will be
from First Nations background (18-30 yrs) and from all other ethnic backgrounds, stratified
into two intervention groups and two wait-list control groups.
Primary outcome is self reported depression using the Beck Depression Inventory II while
secondary outcomes include self reported anxiety (Beck Anxiety Inventory), depression (Quick
Inventory of Depressive Symptomatology, 24-item Hamilton Rating Scale for Depression
(HRSD-24)), pain (Brief Pain Inventory) mindfulness (Five-Facet Mindfulness Questionnaire)
and intervention costs.
If hypotheses are confirmed that youth can be effectively treated with online MB-CBT at
reduced costs, effective treatment can be delivered to greater numbers with less geographic
restriction.
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