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NCT03908606 Clinical Trial

Serum Hs-CRP in Periodontitis Patients With or Without Diabetes

Diabetes Mellitus, Type 2 Clinical Trial

Official title:
Prognostic Value of Serum Hs-CRP in Periodontitis Patients With or Without Type 2 Diabetes Following Non-surgical Periodontal Therapy

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03908606
Other study ID # 1281976
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date April 11, 2018
Est. completion date January 2, 2019

Study information
Verified date April 2019
Source Cairo University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

the aim of this study was to assess serum levels of high sensitivity c reactive protein in periodontitis patients with and without type 2 diabetes in a trial to analyze its prognostic effect following non-surgical periodontal therapy.

Description:

Periodontitis and diabetes are chronic disorders with a two-way correlation as they can both stimulate an inflammatory response with subsequent formation of inflammatory mediators and cytokines. C reactive protein is an inflammatory plasma marker having a role in the systemic reaction to inflammation. thus, our aim in the current study was to evaluate serum levels of high sensitivity c reactive protein in periodontitis patients with and without type 2 diabetes in a trial to analyze its prognostic effect following non-surgical periodontal therapy. A total of 60 patients were enrolled in this study. ELISA was used for determination of hs- CRP. Non- surgical periodontal therapy was carried out for all periodontitis patients.

Recruitment information / eligibility
Status Completed
Enrollment 60
Est. completion date January 2, 2019
Est. primary completion date January 2, 2019
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group N/A and older
Eligibility Inclusion Criteria:

1. Diabetic patients type 2

2. Periodontitis patients

Exclusion Criteria:

1. Smokers

2. Pregnant females

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Scaling and root planing
Supra and subgingival scaling and root planing.

Locations
Country Name City State
Egypt Cairo University Cairo

Sponsors (1)
Lead Sponsor Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary clinical attachment level gain in clinical attachment level 3 months
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