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NCT05875519 Clinical Trial

Healing Process and Blood Sugar Level Following Local Anesthetic Infiltration With and Without Vasoconstrictor

Diabetes Clinical Trial

Official title:
Evaluation of Healing Process and Blood Sugar Level Following Local Anesthetic Infiltration With and Without Vasoconstrictor for Extraction of Maxillary Teeth in Diabetic Patients Double Blind Randomized Clinical Trial

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT05875519
Other study ID # 714
Secondary ID
Status Active, not recruiting
Phase N/A
First received
Last updated
Start date May 1, 2023
Est. completion date May 30, 2023

Study information
Verified date May 2023
Source Minia University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Evaluating the healing of the extraction socket and the glycemic levels before, and after injection of local anesthesia with and without vasoconstrictor in diabetic patients

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 40
Est. completion date May 30, 2023
Est. primary completion date May 15, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 20 Years to 60 Years
Eligibility Inclusion Criteria: - Inclusion criteria patients over 20 years and under 60 years of age - DM controlled by medication - Requiring a tooth extraction in the maxilla, with an indication of the intra-alveolar technique for periodontal reasons. - Only participants that are willing to control and record blood glucose level throughout the study period. Exclusion Criteria: - Patients with any significant medical condition (besides DM) - Alcoholic individuals - Patients on drugs that affect the central nervous systems - Patients who reported the use of drugs that might interfere with pain sensitivity - Pregnant and lactating women - Patients with hypersensitivity to local anesthetics or non-steroidal anti-inflammatory drugs (NSAIDs).

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Local anaesthesia with vasocontrictor (Mepivacaine hydrochloride 20 mg (2%) + Levonordefrin hydrochloride 0.06 mg)
Mepivacaine hydrochloride 20 mg (2%) + Levonordefrin hydrochloride 0.06 mg

Locations
Country Name City State
Egypt Faculty of Dentistry, Minia University Minya

Sponsors (1)
Lead Sponsor Collaborator
Minia University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Glycemic level recorded before local anesthesia administration and 30 minutes following local anesthesia injection using glucometer 30 minutes
Secondary Healing score of the extraction socket 21 days
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