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Diabetes Mellitus, Type 2 clinical trials

View clinical trials related to Diabetes Mellitus, Type 2.

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NCT ID: NCT04444375 Completed - Diabetes Mellitus Clinical Trials

Plantar Pain, Balance and Foot Function in Individuals With Diabetes Mellitus

Start date: December 1, 2017
Phase:
Study type: Observational

Diabetes Mellitus (DM) and increase of body mass index (BMI) are two one of the most common risk factors for plantar pain and related disability. The aim of our study was to evaluate the relationship between plantar pain, balance and foot function in diabetic DM patients has with different BMI.

NCT ID: NCT04443842 Completed - Clinical trials for Diabetes Mellitus, Type 2

Behavioural Economics-based Incentives in Adults With Type 2 Diabetes Pilot Study

Start date: November 1, 2020
Phase: N/A
Study type: Interventional

A feasibility pilot study of a randomised control trial of adults newly diagnosed with type 2 diabetes to compare the effectiveness of financial and social incentives on healthy lifestyle behaviour.

NCT ID: NCT04442698 Completed - Diabetes Clinical Trials

Tailored Bilio-Pancreatic Limb and HbA1c 10 Years Post Mini-Gastric Bypass

BPLLvHbA1c
Start date: January 1, 2008
Phase:
Study type: Observational

Diabetes is now or soon will be a worldwide epidemic. Diabetes has impact on both healthcare costs in addition to the costs in human lives, suffering and disability. Treatment that lowers Hemoglobin A1c (HbA1c) improved outcomes. Studies have demonstrated that both general surgery and bariatric procedures may improve or reverse diabetes. In several studies the Billroth II reconstruction following gastrectomy was the most effective surgical technique in improving or reversing Diabetes. The purpose of this study is to analyze the outcomes of the Mini-Gastric Bypass-Original Technique (MGB-OT) version of the One Anastomosis Bypass (OAGB) to investigate the association of a "Tailored" Bilio-pancreatic Limb Length (BPLL) with the HbA1c changes.

NCT ID: NCT04439474 Completed - Clinical trials for Diabetes Mellitus, Type 2

Determining the Effect of Vitamin D, Dyslipidemia and Microvascular in Patients With Type 2 Diabetes

Start date: October 10, 2018
Phase: N/A
Study type: Interventional

This study looked at the effect of vitamin D levels on the complications of type 2 diabetes and the fat profile of patients with diabetes.Participants in this study were divided into two groups. One group included participants with vitamin D deficiency and the other group did not.The first group receives 50,000 units of oral vitamin D 3 daily for up to 8 days.

NCT ID: NCT04438018 Completed - Clinical trials for Diabetes Mellitus, Type 2

Towards a Better Understanding of Diabetes Distress, Depression and Poor Glycaemic Control in T2DM

DIA-LINK2
Start date: July 1, 2020
Phase:
Study type: Observational

DIA-LINK2 is a prospective observational study analysing longitudinal associations and mediating links between diabetes distress (DD), depressive symptoms (DS) and glycaemic outcomes in people with type 2 diabetes (T2DM). A total of 200 people with T2DM with different levels of DD and DS are to be enrolled. At baseline, all participants are assessed for DD and DS, psychological and stress-related variables, self-reported self-management, HbA1c and inflammatory markers. This is followed by a 4-week ambulatory assessment period including continuous glucose monitoring (CGM), continuous activity tracking and daily event sampling regarding sleep, stress levels, mood and diabetes-related issues; additionally, cortisol levels are assessed on four days within this period. Three months after baseline, a follow-up assessment covers DD and DS levels, stress-related variables, self-reported self-management, HbA1c and final CGM assessment. The analyses aim to establish risk factors/protective factors regarding DD and DS, their relative impact on glycaemic outcomes and potential mediation of the associations by behavioural (e.g. self-management, physical activity), physical (e.g. heart rate variability, inflammatory activity) and mental variables (subjective stress level) in T2DM.

NCT ID: NCT04436900 Completed - Clinical trials for Diabetes Mellitus, Type 2

Evaluation of Macular Structural and Functional Function Following Extensive Retinal Laser Therapy in Patients With Proliferative Diabetic Retinopathy

Start date: April 10, 2018
Phase: N/A
Study type: Interventional

The present study is a semi-experimental clinical trial that 20 patients (40 eyes) with PDR underwent PRP with ARC with a spot number of 1,200 to 1,500 per eye and spot size 500 micron with a duration of 200 ms. The variables of contrast sensitivity, macula thickness under fovea , BCVA, the width of thyroid under fovea , RNFL thickness in the four areas around the disc, and the quality of life questionnaire of all patients were recorded at the beginning of the study.Retinal and choroid under fovea thickness and RNFL thickness were assessed in four areas, one week and one month after the end of treatment, and all the variables mentioned earlier were evaluated three months after PRP surgery. This study is single group that the outcomes are compared before and after the intervention

NCT ID: NCT04430660 Completed - Diabetes Clinical Trials

Evaluating Glial Acetate Metabolism as a Biomarker of Hypoglycemic Complications in Diabetic Patients

GLEAM
Start date: August 19, 2020
Phase: N/A
Study type: Interventional

A recent pilot study, GLIMPSE (NCT02690168), was recently completed which demonstrated that the rate of glial acetate metabolism (GAM) is closely associated with susceptibility to fasting-induced hypoglycemia in healthy adults. Insulin-induced hypoglycemia is a common complication of diabetes treatment and is a major barrier to the maintenance of healthy glucose levels in individuals with diabetes. The primary purpose of the study is to test the proof-of-concept that there is an association between the rate of GAM and susceptibility to insulin-induced hypoglycemia. In order to observe such a relationship the rate of GAM will be measured in a patient population known to frequently experience hypoglycemia, i.e., individuals with type 1 diabetes mellitus (T1DM).

NCT ID: NCT04430608 Completed - Covid-19 Clinical Trials

Remote Continues Glucose Monitoring During the COVID-19 Pandemic in Quarantined Hospitalized Patients

CGM-ISO
Start date: May 25, 2020
Phase: N/A
Study type: Interventional

This is a randomized controlled trial of isolated patients with diabetes admitted to Nordsjællands Hospital with or without COVID-19-pneumonia. A continuous glucose monitoring (CGM) based system with transmission of glucose data to a central system is used for remote monitoring of glucose levels and compared to standard finger-prick glucose. Blinded (to patients) CGM is mounted in the finger-prick group.

NCT ID: NCT04427982 Completed - Diabetes Clinical Trials

Dance and Diabetes/Prediabetes Self-Management

Start date: September 3, 2020
Phase: N/A
Study type: Interventional

The Dance for Diabetes program was designed as a community service project for the North Carolina Albert Schweitzer Fellowship. The purpose of this research is to evaluate the effectiveness of the project and its impact on participants. This study will assess whether a group dance workshop along with diabetes education can help people with diabetes and prediabetes.

NCT ID: NCT04426474 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study of LY3502970 in Participants With Type 2 Diabetes

Start date: October 8, 2020
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to learn more about the safety of LY3502970 and any side effects that might be associated with it. Blood tests will be done to measure how much LY3502970 is in the bloodstream, how long it takes the body to eliminate it, and how it affects blood sugar. Participation could last up to 18 weeks and may include up to 14 visits (including three overnight stays) in the study center.