Melatonin Decreases Eye Pressure in Normotensive Patients

Status Completed

Clinical Trial Summary

Agomelatine is a melatonin drug used to treat depressive disorder. Agomelatine may also some effects on ocular pressures. In this study, we aimed to demonstrate that melatonin decreases intraocular pressures when given depressive patients.

Clinical Trial Description

Melatonin has been shown to be effective to decrease intraocular pressure in experimental animal researches. Agomelatine is a melatonin derivative drug approved for the treatment of depression, which is also available in our country. Depending on animal experiments, it can be assumed that agomelatine can decrease intraocular pressure. Demonstrating that agomelatine is effective to reduce eye pressure may give a concurrent treatment of depressive patients with glaucoma. With this it may be possible to treat both diseases at the same time with single drug. In this study, the researchers intended to investigate the changes in ocular tension in normotensive depressive patients treated with agomelatine. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03193112
Study type	Observational
Source	Kahramanmaras Sutcu Imam University
Contact
Status	Completed
Phase
Start date	June 16, 2017
Completion date	June 15, 2018

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