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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT00879853
Other study ID # UCSF Academic Senate Grant
Secondary ID
Status Completed
Phase N/A
First received
Last updated

Study information

Verified date November 2023
Source University of California, San Francisco
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The enormous global burden of mental illness has been estimated through the publication of the Global Burden of Disease Study, adding momentum to refugee mental health studies (1,2). As research confirms that high levels of Posttraumatic Stress Disorder (PTSD) and depression occur in post-conflict settings, it is essential to develop effective treatment for psychological trauma in refugee populations recovering from mass violence (3-4). PTSD and depression are risk factors for anger, interpersonal discord and violence, not only among those who have trauma and depression, but also among their spouses and children (5-9). This "infectious" model of trauma/violence is critically important in the setting of ethnic conflict, as increased levels of interpersonal violence within the afflicted community hinder its recovery and fuel future cycles of conflict. To date, there has been little research on the interpersonal effects of trauma among refugee populations. The proposed research is a pilot and randomized controlled trial of "Interpersonal Therapy" (IPT) for Sudanese refugees living in Cairo. IPT, a very effective therapy for depression, has been adapted for PTSD treatment and sub-Saharan Africa settings (10-12). Measures will evaluate success of the treatment not only in terms of individual PTSD and depression symptoms, but also with respect to interpersonal conflict. Hypotheses: (1) After IPT intervention, Sudanese refugees will have lower levels of depression and trauma symptoms compared to wait list controls (2) After IPT intervention, Sudanese refugees will have lower levels of interpersonal violence compared to wait list controls.


Recruitment information / eligibility

Status Completed
Enrollment 0
Est. completion date
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: 1. Age greater than 18 years; 2. Absence of cognitive dysfunction which requires a higher level of care and/or interferes with ability to participate in IPT; 3. Absence of severe thought or mood disorder symptoms which requires a higher level of care and/or interferes with ability to participate in IPT; 4. Absence of drug and alcohol dependence; 5. HTQ score of 2.3 or greater; 6. Ability to attend twice a week therapy sessions for 4 weeks and return for regular screening; 7. Ability to give verbal informed consent . Exclusion Criteria: 1. Unable to give informed consent; 2. Age less than 18; 3. Cognitive dysfunction which requires a higher level of care and/or interferes with ability to participate in IPT; 4. Severe thought or mood disorder symptoms which requires a higher level of care and/or interferes with ability to participate in IPT; 5. Drug or alcohol dependence in the past 6 months; 6. HTQ score less than 2.5; 7. Inability to attend twice a week therapy sessions for 4 weeks and return for regular screening .

Study Design


Intervention

Behavioral:
Interpersonal Therapy


Locations

Country Name City State
Egypt Ma'an Organization Cairo

Sponsors (2)

Lead Sponsor Collaborator
University of California, San Francisco Ma'an Organization

Country where clinical trial is conducted

Egypt, 

Outcome

Type Measure Description Time frame Safety issue
Primary Post-traumatic Stress Disorder Symptoms
Secondary Depression Symptoms
Secondary Anger
Secondary Household Conflict/Violence
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